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Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial.
Hochberg MC, Guermazi A, Guehring H, Aydemir A, Wax S, Fleuranceau-Morel P, Reinstrup Bihlet A, Byrjalsen I, Ragnar Andersen J, Eckstein F. Hochberg MC, et al. Among authors: guehring h. JAMA. 2019 Oct 8;322(14):1360-1370. doi: 10.1001/jama.2019.14735. JAMA. 2019. PMID: 31593273 Free PMC article. Clinical Trial.
Low levels of type II collagen formation (PRO-C2) are associated with response to sprifermin: a pre-defined, exploratory biomarker analysis from the FORWARD study.
Bay-Jensen AC, Manginelli AA, Karsdal M, Luo Y, He Y, Michaelis M, Guehring H, Ladel C. Bay-Jensen AC, et al. Among authors: guehring h. Osteoarthritis Cartilage. 2022 Jan;30(1):92-99. doi: 10.1016/j.joca.2021.10.008. Epub 2021 Nov 1. Osteoarthritis Cartilage. 2022. PMID: 34737064 Free article. Clinical Trial.
34 results