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Mycobacterium tuberculosis requires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism.
Serafini A, Tan L, Horswell S, Howell S, Greenwood DJ, Hunt DM, Phan MD, Schembri M, Monteleone M, Montague CR, Britton W, Garza-Garcia A, Snijders AP, VanderVen B, Gutierrez MG, West NP, de Carvalho LPS. Serafini A, et al. Among authors: monteleone m. Mol Microbiol. 2019 Oct;112(4):1284-1307. doi: 10.1111/mmi.14362. Epub 2019 Aug 23. Mol Microbiol. 2019. PMID: 31389636 Free PMC article.
Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages.
Kapetanovic R, Bokil NJ, Achard ME, Ong CL, Peters KM, Stocks CJ, Phan MD, Monteleone M, Schroder K, Irvine KM, Saunders BM, Walker MJ, Stacey KJ, McEwan AG, Schembri MA, Sweet MJ. Kapetanovic R, et al. Among authors: monteleone m. FASEB J. 2016 May;30(5):1901-12. doi: 10.1096/fj.201500061. Epub 2016 Feb 2. FASEB J. 2016. PMID: 26839376
In summary, our study provides new insights at the cellular level into the well-documented effects of zinc in promoting host defense against infectious disease, as well as the complex host subversion strategies employed by S Typhimurium to combat this pathway.-Kapetanovic, R., Bo …
In summary, our study provides new insights at the cellular level into the well-documented effects of zinc in promoting host defense against …
A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence.
Kim JH, O'Brien KM, Sharma R, Boshoff HI, Rehren G, Chakraborty S, Wallach JB, Monteleone M, Wilson DJ, Aldrich CC, Barry CE 3rd, Rhee KY, Ehrt S, Schnappinger D. Kim JH, et al. Among authors: monteleone m. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19095-100. doi: 10.1073/pnas.1315860110. Epub 2013 Nov 4. Proc Natl Acad Sci U S A. 2013. PMID: 24191058 Free PMC article.
NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5.
Baker PJ, Boucher D, Bierschenk D, Tebartz C, Whitney PG, D'Silva DB, Tanzer MC, Monteleone M, Robertson AA, Cooper MA, Alvarez-Diaz S, Herold MJ, Bedoui S, Schroder K, Masters SL. Baker PJ, et al. Among authors: monteleone m. Eur J Immunol. 2015 Oct;45(10):2918-26. doi: 10.1002/eji.201545655. Epub 2015 Aug 24. Eur J Immunol. 2015. PMID: 26173988 Free article.
Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.
Boucher D, Monteleone M, Coll RC, Chen KW, Ross CM, Teo JL, Gomez GA, Holley CL, Bierschenk D, Stacey KJ, Yap AS, Bezbradica JS, Schroder K. Boucher D, et al. Among authors: monteleone m. J Exp Med. 2018 Mar 5;215(3):827-840. doi: 10.1084/jem.20172222. Epub 2018 Feb 6. J Exp Med. 2018. PMID: 29432122 Free PMC article.
174 results