Geng P - Search Results

1

Development of the triazole-fused pyrimidine derivatives as highly potent and reversible inhibitors of histone lysine specific demethylase 1 (LSD1/KDM1A).

Li Z, Ding L, Li Z, Wang Z, Suo F, Shen D, Zhao T, Sun X, Wang J, Liu Y, Ma L, Zhao B, Geng P, Yu B, Zheng Y, Liu H. Li Z, et al. Among authors: geng p. Acta Pharm Sin B. 2019 Jul;9(4):794-808. doi: 10.1016/j.apsb.2019.01.001. Epub 2019 Jan 5. Acta Pharm Sin B. 2019. PMID: 31384539 Free PMC article.

2

Discovery of [1,2,3]Triazolo[4,5-d]pyrimidine Derivatives as Novel LSD1 Inhibitors.

Li ZH, Liu XQ, Geng PF, Suo FZ, Ma JL, Yu B, Zhao TQ, Zhou ZQ, Huang CX, Zheng YC, Liu HM. Li ZH, et al. ACS Med Chem Lett. 2017 Mar 6;8(4):384-389. doi: 10.1021/acsmedchemlett.6b00423. eCollection 2017 Apr 13. ACS Med Chem Lett. 2017. PMID: 28435523 Free PMC article.

3

Design, synthesis and biological evaluation of [1,2,3]triazolo[4,5-d]pyrimidine derivatives possessing a hydrazone moiety as antiproliferative agents.

Li ZH, Yang DX, Geng PF, Zhang J, Wei HM, Hu B, Guo Q, Zhang XH, Guo WG, Zhao B, Yu B, Ma LY, Liu HM. Li ZH, et al. Eur J Med Chem. 2016 Nov 29;124:967-980. doi: 10.1016/j.ejmech.2016.10.022. Epub 2016 Oct 14. Eur J Med Chem. 2016. PMID: 27771599

4

Identification of thiazolo[5,4-d]pyrimidine derivatives as potent antiproliferative agents through the drug repurposing strategy.

Li ZH, Zhang J, Liu XQ, Geng PF, Ma JL, Wang B, Zhao TQ, Zhao B, Wei HM, Wang C, Fu DJ, Yu B, Liu HM. Li ZH, et al. Eur J Med Chem. 2017 Jul 28;135:204-212. doi: 10.1016/j.ejmech.2017.04.056. Epub 2017 Apr 22. Eur J Med Chem. 2017. PMID: 28456031

5

Design, synthesis and antiproliferative activity of thiazolo[5,4-d]pyrimidine derivatives through the atom replacement strategy.

Li ZH, Liu XQ, Geng PF, Zhang J, Ma JL, Wang B, Zhao TQ, Zhao B, Zhang XH, Yu B, Liu HM. Li ZH, et al. Eur J Med Chem. 2017 Sep 29;138:1034-1041. doi: 10.1016/j.ejmech.2017.07.039. Epub 2017 Jul 22. Eur J Med Chem. 2017. PMID: 28759876

6

Design, synthesis and preliminary antiproliferative activity studies of new diheteroaryl thioether derivatives.

Li ZH, Liu XQ, Zhao TQ, Geng PF, Liu Y, Zhao B, Guo WG, Yu B, Liu HM. Li ZH, et al. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4377-4382. doi: 10.1016/j.bmcl.2017.08.021. Epub 2017 Aug 18. Bioorg Med Chem Lett. 2017. PMID: 28838695

7

Design, synthesis and preliminary biological evaluation of new [1,2,3]triazolo[4,5-d]pyrimidine/thiourea hybrids as antiproliferative agents.

Li ZH, Liu XQ, Zhao TQ, Geng PF, Guo WG, Yu B, Liu HM. Li ZH, et al. Eur J Med Chem. 2017 Oct 20;139:741-749. doi: 10.1016/j.ejmech.2017.08.042. Epub 2017 Aug 31. Eur J Med Chem. 2017. PMID: 28863355

8

Synthesis and preliminary antiproliferative activity of new pteridin-7(8H)-one derivatives.

Li ZH, Zhao TQ, Liu XQ, Zhao B, Wang C, Geng PF, Cao YQ, Fu DJ, Jiang LP, Yu B, Liu HM. Li ZH, et al. Eur J Med Chem. 2018 Jan 1;143:1396-1405. doi: 10.1016/j.ejmech.2017.10.037. Epub 2017 Oct 16. Eur J Med Chem. 2018. PMID: 29113745

9

Design, synthesis and preliminary biological evaluation of 5,8-dihydropteridine-6,7-diones that induce apoptosis and suppress cell migration.

Geng PF, Wang CC, Li ZH, Hu XN, Zhao TQ, Fu DJ, Zhao B, Yu B, Liu HM. Geng PF, et al. Eur J Med Chem. 2018 Jan 1;143:1959-1967. doi: 10.1016/j.ejmech.2017.11.009. Epub 2017 Nov 5. Eur J Med Chem. 2018. PMID: 29133051

10

Design, synthesis and in vitro biological evaluation of novel [1,2,3]triazolo[4,5-d]pyrimidine derivatives containing a thiosemicarbazide moiety.

Geng PF, Liu XQ, Zhao TQ, Wang CC, Li ZH, Zhang J, Wei HM, Hu B, Ma LY, Liu HM. Geng PF, et al. Eur J Med Chem. 2018 Feb 25;146:147-156. doi: 10.1016/j.ejmech.2018.01.031. Epub 2018 Jan 17. Eur J Med Chem. 2018. PMID: 29407946

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