Mutagenesis mapping of the protein-protein interaction underlying FusB-type fusidic acid resistance.
Cox G, Edwards TA, O'Neill AJ.
Cox G, et al.
Antimicrob Agents Chemother. 2013 Oct;57(10):4640-4. doi: 10.1128/AAC.00198-13. Epub 2013 Jul 8.
Antimicrob Agents Chemother. 2013.
PMID: 23836182
Free PMC article.
FusB-type proteins represent the predominant mechanism of resistance to fusidic acid in staphylococci and act by binding to and modulating the function of the drug target (elongation factor G [EF-G]). To gain further insight into this antibiotic resistance mechanism …
FusB-type proteins represent the predominant mechanism of resistance to fusidic acid in staphylococci and act by binding to and modulating t …