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Page 1
IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma.
Kofuji S, Hirayama A, Eberhardt AO, Kawaguchi R, Sugiura Y, Sampetrean O, Ikeda Y, Warren M, Sakamoto N, Kitahara S, Yoshino H, Yamashita D, Sumita K, Wolfe K, Lange L, Ikeda S, Shimada H, Minami N, Malhotra A, Morioka S, Ban Y, Asano M, Flanary VL, Ramkissoon A, Chow LML, Kiyokawa J, Mashimo T, Lucey G, Mareninov S, Ozawa T, Onishi N, Okumura K, Terakawa J, Daikoku T, Wise-Draper T, Majd N, Kofuji K, Sasaki M, Mori M, Kanemura Y, Smith EP, Anastasiou D, Wakimoto H, Holland EC, Yong WH, Horbinski C, Nakano I, DeBerardinis RJ, Bachoo RM, Mischel PS, Yasui W, Suematsu M, Saya H, Soga T, Grummt I, Bierhoff H, Sasaki AT. Kofuji S, et al. Among authors: wolfe k. Nat Cell Biol. 2019 Aug;21(8):1003-1014. doi: 10.1038/s41556-019-0363-9. Epub 2019 Aug 1. Nat Cell Biol. 2019. PMID: 31371825 Free PMC article.
Identification of lysine methylation in the core GTPase domain by GoMADScan.
Yoshino H, Yin G, Kawaguchi R, Popov KI, Temple B, Sasaki M, Kofuji S, Wolfe K, Kofuji K, Okumura K, Randhawa J, Malhotra A, Majd N, Ikeda Y, Shimada H, Kahoud ER, Haviv S, Iwase S, Asara JM, Campbell SL, Sasaki AT. Yoshino H, et al. Among authors: wolfe k. PLoS One. 2019 Aug 7;14(8):e0219436. doi: 10.1371/journal.pone.0219436. eCollection 2019. PLoS One. 2019. PMID: 31390367 Free PMC article.
Anti-Tumor Potential of IMP Dehydrogenase Inhibitors: A Century-Long Story.
Naffouje R, Grover P, Yu H, Sendilnathan A, Wolfe K, Majd N, Smith EP, Takeuchi K, Senda T, Kofuji S, Sasaki AT. Naffouje R, et al. Among authors: wolfe k. Cancers (Basel). 2019 Sep 11;11(9):1346. doi: 10.3390/cancers11091346. Cancers (Basel). 2019. PMID: 31514446 Free PMC article. Review.
Correction: Identification of lysine methylation in the core GTPase domain by GoMADScan.
Yoshino H, Yin G, Kawaguchi R, Popov KI, Temple B, Sasaki M, Kofuji S, Wolfe K, Kofuji K, Okumura K, Randhawa J, Malhotra A, Majd N, Ikeda Y, Shimada H, Kahoud ER, Haviv S, Iwase S, Asara JM, Campbell SL, Sasaki AT. Yoshino H, et al. Among authors: wolfe k. PLoS One. 2019 Oct 22;14(10):e0224443. doi: 10.1371/journal.pone.0224443. eCollection 2019. PLoS One. 2019. PMID: 31639175 Free PMC article.
A high dose KRP203 induces cytoplasmic vacuoles associated with altered phosphoinositide segregation and endosome expansion.
Kofuji S, Wolfe K, Sumita K, Kageyama S, Yoshino H, Hirota Y, Ogawa-Iio A, Kanoh H, Sasaki M, Kofuji K, Davis MI, Pragani R, Shen M, Boxer MB, Nakatsu F, Nigorikawa K, Sasaki T, Takeuchi K, Senda T, Kim SM, Edinger AL, Simeonov A, Sasaki AT. Kofuji S, et al. Among authors: wolfe k. Biochem Biophys Res Commun. 2024 Jul 23;718:149981. doi: 10.1016/j.bbrc.2024.149981. Epub 2024 Apr 27. Biochem Biophys Res Commun. 2024. PMID: 38735134
Enterobactin inhibits microbiota-dependent activation of AhR to promote bacterial sepsis in mice.
Keskey RC, Xiao J, Hyoju S, Lam A, Kim D, Sidebottom AM, Zaborin A, Dijkstra A, Meltzer R, Thakur A, Zhang K, Chen HJ, Beloborodova NV, Pautova AK, Wolfe K, Patel B, Thewissen R, Zaborina O, Alverdy JC. Keskey RC, et al. Among authors: wolfe k. Nat Microbiol. 2025 Jan 8. doi: 10.1038/s41564-024-01882-9. Online ahead of print. Nat Microbiol. 2025. PMID: 39779878
576 results