Ambudkar SV - Search Results

1

Synthesis and Characterization of Bodipy-FL-Cyclosporine A as a Substrate for Multidrug Resistance-Linked P-Glycoprotein (ABCB1).

Sajid A, Raju N, Lusvarghi S, Vahedi S, Swenson RE, Ambudkar SV. Sajid A, et al. Among authors: ambudkar sv. Drug Metab Dispos. 2019 Oct;47(10):1013-1023. doi: 10.1124/dmd.119.087734. Epub 2019 Aug 1. Drug Metab Dispos. 2019. PMID: 31371421 Free PMC article.

2

Characterization of phosphorylation-defective mutants of human P-glycoprotein expressed in mammalian cells.

Germann UA, Chambers TC, Ambudkar SV, Licht T, Cardarelli CO, Pastan I, Gottesman MM. Germann UA, et al. Among authors: ambudkar sv. J Biol Chem. 1996 Jan 19;271(3):1708-16. doi: 10.1074/jbc.271.3.1708. J Biol Chem. 1996. PMID: 8576173 Free article.

3

P-glycoprotein and multidrug resistance.

Gottesman MM, Pastan I, Ambudkar SV. Gottesman MM, et al. Among authors: ambudkar sv. Curr Opin Genet Dev. 1996 Oct;6(5):610-7. doi: 10.1016/s0959-437x(96)80091-8. Curr Opin Genet Dev. 1996. PMID: 8939727 Review.

4

Relation between the turnover number for vinblastine transport and for vinblastine-stimulated ATP hydrolysis by human P-glycoprotein.

Ambudkar SV, Cardarelli CO, Pashinsky I, Stein WD. Ambudkar SV, et al. J Biol Chem. 1997 Aug 22;272(34):21160-6. doi: 10.1074/jbc.272.34.21160. J Biol Chem. 1997. PMID: 9261121 Free article.

5

Mechanism of action of human P-glycoprotein ATPase activity. Photochemical cleavage during a catalytic transition state using orthovanadate reveals cross-talk between the two ATP sites.

Hrycyna CA, Ramachandra M, Ambudkar SV, Ko YH, Pedersen PL, Pastan I, Gottesman MM. Hrycyna CA, et al. Among authors: ambudkar sv. J Biol Chem. 1998 Jul 3;273(27):16631-4. doi: 10.1074/jbc.273.27.16631. J Biol Chem. 1998. PMID: 9642211 Free article.

6

Biochemical, cellular, and pharmacological aspects of the multidrug transporter.

Ambudkar SV, Dey S, Hrycyna CA, Ramachandra M, Pastan I, Gottesman MM. Ambudkar SV, et al. Annu Rev Pharmacol Toxicol. 1999;39:361-98. doi: 10.1146/annurev.pharmtox.39.1.361. Annu Rev Pharmacol Toxicol. 1999. PMID: 10331089 Review.

7

Correlation between steady-state ATP hydrolysis and vanadate-induced ADP trapping in Human P-glycoprotein. Evidence for ADP release as the rate-limiting step in the catalytic cycle and its modulation by substrates.

Kerr KM, Sauna ZE, Ambudkar SV. Kerr KM, et al. Among authors: ambudkar sv. J Biol Chem. 2001 Mar 23;276(12):8657-64. doi: 10.1074/jbc.M010044200. Epub 2000 Dec 19. J Biol Chem. 2001. PMID: 11121420 Free article.

8

Evidence for the vectorial nature of drug (substrate)-stimulated ATP hydrolysis by human P-glycoprotein.

Sauna ZE, Smith MM, Müller M, Ambudkar SV. Sauna ZE, et al. Among authors: ambudkar sv. J Biol Chem. 2001 Sep 7;276(36):33301-4. doi: 10.1074/jbc.C100369200. Epub 2001 Jul 12. J Biol Chem. 2001. PMID: 11451943 Free article.

9

Transport activity and surface expression of the Na+-Ca2+ exchanger NCX1 are inhibited by the immunosuppressive agent cyclosporin A and by the nonimmunosuppressive agent PSC833.

Kimchi-Sarfaty C, Kasir J, Ambudkar SV, Rahamimoff H. Kimchi-Sarfaty C, et al. Among authors: ambudkar sv. J Biol Chem. 2002 Jan 25;277(4):2505-10. doi: 10.1074/jbc.M109154200. Epub 2001 Nov 7. J Biol Chem. 2002. PMID: 11700317 Free article.

10

The mechanism of action of multidrug-resistance-linked P-glycoprotein.

Sauna ZE, Smith MM, Müller M, Kerr KM, Ambudkar SV. Sauna ZE, et al. Among authors: ambudkar sv. J Bioenerg Biomembr. 2001 Dec;33(6):481-91. doi: 10.1023/a:1012875105006. J Bioenerg Biomembr. 2001. PMID: 11804190 Review.

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