Tiedje C - Search Results

1

Cooperative and distinct functions of MK2 and MK3 in the regulation of the macrophage transcriptional response to lipopolysaccharide.

Ehlting C, Rex J, Albrecht U, Deenen R, Tiedje C, Köhrer K, Sawodny O, Gaestel M, Häussinger D, Bode JG. Ehlting C, et al. Among authors: tiedje c. Sci Rep. 2019 Jul 30;9(1):11021. doi: 10.1038/s41598-019-46791-8. Sci Rep. 2019. PMID: 31363109 Free PMC article.

2

MAPKAP kinase 2 regulates IL-10 expression and prevents formation of intrahepatic myeloid cell aggregates during cytomegalovirus infections.

Ehlting C, Trilling M, Tiedje C, Le-Trilling VTK, Albrecht U, Kluge S, Zimmermann A, Graf D, Gaestel M, Hengel H, Häussinger D, Bode JG. Ehlting C, et al. Among authors: tiedje c. J Hepatol. 2016 Feb;64(2):380-389. doi: 10.1016/j.jhep.2015.08.012. Epub 2015 Aug 20. J Hepatol. 2016. PMID: 26299622

3

MAPKAP kinases MK2 and MK3 in inflammation: complex regulation of TNF biosynthesis via expression and phosphorylation of tristetraprolin.

Ronkina N, Menon MB, Schwermann J, Tiedje C, Hitti E, Kotlyarov A, Gaestel M. Ronkina N, et al. Among authors: tiedje c. Biochem Pharmacol. 2010 Dec 15;80(12):1915-20. doi: 10.1016/j.bcp.2010.06.021. Epub 2010 Jun 23. Biochem Pharmacol. 2010. PMID: 20599781 Review.

4

Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2.

Trulley P, Snieckute G, Bekker-Jensen D, Menon MB, Freund R, Kotlyarov A, Olsen JV, Diaz-Muñoz MD, Turner M, Bekker-Jensen S, Gaestel M, Tiedje C. Trulley P, et al. Among authors: tiedje c. Cell Rep. 2019 Jun 4;27(10):2859-2870.e6. doi: 10.1016/j.celrep.2019.05.024. Cell Rep. 2019. PMID: 31167133 Free article.

5

The Role of TTP Phosphorylation in the Regulation of Inflammatory Cytokine Production by MK2/3.

Ronkina N, Shushakova N, Tiedje C, Yakovleva T, Tollenaere MAX, Scott A, Batth TS, Olsen JV, Helmke A, Bekker-Jensen SH, Clark AR, Kotlyarov A, Gaestel M. Ronkina N, et al. Among authors: tiedje c. J Immunol. 2019 Oct 15;203(8):2291-2300. doi: 10.4049/jimmunol.1801221. Epub 2019 Sep 16. J Immunol. 2019. PMID: 31527197

6

TRIF signaling stimulates translation of TNF-alpha mRNA via prolonged activation of MK2.

Gais P, Tiedje C, Altmayr F, Gaestel M, Weighardt H, Holzmann B. Gais P, et al. Among authors: tiedje c. J Immunol. 2010 May 15;184(10):5842-8. doi: 10.4049/jimmunol.0902456. Epub 2010 Apr 7. J Immunol. 2010. PMID: 20375303

7

Molecular mechanisms of phosphorylation-regulated TTP (tristetraprolin) action and screening for further TTP-interacting proteins.

Tiedje C, Kotlyarov A, Gaestel M. Tiedje C, et al. Biochem Soc Trans. 2010 Dec;38(6):1632-7. doi: 10.1042/BST0381632. Biochem Soc Trans. 2010. PMID: 21118139

8

The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation.

Tiedje C, Ronkina N, Tehrani M, Dhamija S, Laass K, Holtmann H, Kotlyarov A, Gaestel M. Tiedje C, et al. PLoS Genet. 2012 Sep;8(9):e1002977. doi: 10.1371/journal.pgen.1002977. Epub 2012 Sep 27. PLoS Genet. 2012. PMID: 23028373 Free PMC article.

9

LPS-induced production of TNF-α and IL-6 in mast cells is dependent on p38 but independent of TTP.

Hochdörfer T, Tiedje C, Stumpo DJ, Blackshear PJ, Gaestel M, Huber M. Hochdörfer T, et al. Among authors: tiedje c. Cell Signal. 2013 Jun;25(6):1339-47. doi: 10.1016/j.cellsig.2013.02.022. Epub 2013 Mar 14. Cell Signal. 2013. PMID: 23499908 Free PMC article.

10

Endoplasmic reticulum-associated ubiquitin-conjugating enzyme Ube2j1 is a novel substrate of MK2 (MAPKAP kinase-2) involved in MK2-mediated TNFα production.

Menon MB, Tiedje C, Lafera J, Ronkina N, Konen T, Kotlyarov A, Gaestel M. Menon MB, et al. Among authors: tiedje c. Biochem J. 2013 Dec 1;456(2):163-72. doi: 10.1042/BJ20130755. Biochem J. 2013. PMID: 24020373

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