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mTORC1-PGC1 axis regulates mitochondrial remodeling during reprogramming.
Wang L, Xu X, Jiang C, Ma G, Huang Y, Zhang H, Lai Y, Wang M, Ahmed T, Lin R, Guo W, Luo Z, Li W, Zhang M, Ward C, Qian M, Liu B, Esteban MA, Qin B. Wang L, et al. Among authors: luo z. FEBS J. 2020 Jan;287(1):108-121. doi: 10.1111/febs.15024. Epub 2019 Aug 18. FEBS J. 2020. PMID: 31361392 Free article.
Transcriptional pause release is a rate-limiting step for somatic cell reprogramming.
Liu L, Xu Y, He M, Zhang M, Cui F, Lu L, Yao M, Tian W, Benda C, Zhuang Q, Huang Z, Li W, Li X, Zhao P, Fan W, Luo Z, Li Y, Wu Y, Hutchins AP, Wang D, Tse HF, Schambach A, Frampton J, Qin B, Bao X, Yao H, Zhang B, Sun H, Pei D, Wang H, Wang J, Esteban MA. Liu L, et al. Among authors: luo z. Cell Stem Cell. 2014 Nov 6;15(5):574-88. doi: 10.1016/j.stem.2014.09.018. Epub 2014 Oct 9. Cell Stem Cell. 2014. PMID: 25312495 Free article.
The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters.
Bao X, Wu H, Zhu X, Guo X, Hutchins AP, Luo Z, Song H, Chen Y, Lai K, Yin M, Xu L, Zhou L, Chen J, Wang D, Qin B, Frampton J, Tse HF, Pei D, Wang H, Zhang B, Esteban MA. Bao X, et al. Among authors: luo z. Cell Res. 2015 Jan;25(1):80-92. doi: 10.1038/cr.2014.165. Epub 2014 Dec 16. Cell Res. 2015. PMID: 25512341 Free PMC article.
Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming.
Wu Y, Li Y, Zhang H, Huang Y, Zhao P, Tang Y, Qiu X, Ying Y, Li W, Ni S, Zhang M, Liu L, Xu Y, Zhuang Q, Luo Z, Benda C, Song H, Liu B, Lai L, Liu X, Tse HF, Bao X, Chan WY, Esteban MA, Qin B, Pei D. Wu Y, et al. Among authors: luo z. Nat Cell Biol. 2015 Jun;17(6):715-25. doi: 10.1038/ncb3172. Epub 2015 May 18. Nat Cell Biol. 2015. PMID: 25985393
Fumarylacetoacetate Hydrolase Knock-out Rabbit Model for Hereditary Tyrosinemia Type 1.
Li L, Zhang Q, Yang H, Zou Q, Lai C, Jiang F, Zhao P, Luo Z, Yang J, Chen Q, Wang Y, Newsome PN, Frampton J, Maxwell PH, Li W, Chen S, Wang D, Siu TS, Tam S, Tse HF, Qin B, Bao X, Esteban MA, Lai L. Li L, et al. Among authors: luo z. J Biol Chem. 2017 Mar 17;292(11):4755-4763. doi: 10.1074/jbc.M116.764787. Epub 2017 Jan 4. J Biol Chem. 2017. PMID: 28053091 Free PMC article.
Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells.
Yang J, Wang Y, Zhou T, Wong LY, Tian XY, Hong X, Lai WH, Au KW, Wei R, Liu Y, Cheng LH, Liang G, Huang Z, Fan W, Zhao P, Wang X, Ibañez DP, Luo Z, Li Y, Zhong X, Chen S, Wang D, Li L, Lai L, Qin B, Bao X, Hutchins AP, Siu CW, Huang Y, Esteban MA, Tse HF. Yang J, et al. Among authors: luo z. Stem Cell Reports. 2017 Mar 14;8(3):605-618. doi: 10.1016/j.stemcr.2017.01.027. Epub 2017 Mar 2. Stem Cell Reports. 2017. PMID: 28262545 Free PMC article.
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