Holdsworth SR - Search Results

1

A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity.

Ooi JD, Jiang JH, Eggenhuizen PJ, Chua LL, van Timmeren M, Loh KL, O'Sullivan KM, Gan PY, Zhong Y, Tsyganov K, Shochet LR, Ryan J, Stegeman CA, Fugger L, Reid HH, Rossjohn J, Heeringa P, Holdsworth SR, Peleg AY, Kitching AR. Ooi JD, et al. Among authors: holdsworth sr. Nat Commun. 2019 Jul 29;10(1):3392. doi: 10.1038/s41467-019-11255-0. Nat Commun. 2019. PMID: 31358739 Free PMC article.

2

Th17 cells promote autoimmune anti-myeloperoxidase glomerulonephritis.

Gan PY, Steinmetz OM, Tan DS, O'Sullivan KM, Ooi JD, Iwakura Y, Kitching AR, Holdsworth SR. Gan PY, et al. Among authors: holdsworth sr. J Am Soc Nephrol. 2010 Jun;21(6):925-31. doi: 10.1681/ASN.2009070763. Epub 2010 Mar 18. J Am Soc Nephrol. 2010. PMID: 20299361 Free PMC article.

3

Toll-like receptor 2 induces Th17 myeloperoxidase autoimmunity while Toll-like receptor 9 drives Th1 autoimmunity in murine vasculitis.

Summers SA, Steinmetz OM, Gan PY, Ooi JD, Odobasic D, Kitching AR, Holdsworth SR. Summers SA, et al. Among authors: holdsworth sr. Arthritis Rheum. 2011 Apr;63(4):1124-35. doi: 10.1002/art.30208. Arthritis Rheum. 2011. PMID: 21190299 Free article.

4

The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis.

Ooi JD, Chang J, Hickey MJ, Borza DB, Fugger L, Holdsworth SR, Kitching AR. Ooi JD, et al. Among authors: holdsworth sr. Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):E2615-24. doi: 10.1073/pnas.1210147109. Epub 2012 Sep 5. Proc Natl Acad Sci U S A. 2012. PMID: 22955884 Free PMC article.

5

Myeloperoxidase (MPO)-specific CD4+ T cells contribute to MPO-anti-neutrophil cytoplasmic antibody (ANCA) associated glomerulonephritis.

Gan PY, Holdsworth SR, Kitching AR, Ooi JD. Gan PY, et al. Among authors: holdsworth sr. Cell Immunol. 2013 Mar;282(1):21-7. doi: 10.1016/j.cellimm.2013.04.007. Epub 2013 Apr 25. Cell Immunol. 2013. PMID: 23665205

6

FcγRIIB regulates T-cell autoreactivity, ANCA production, and neutrophil activation to suppress anti-myeloperoxidase glomerulonephritis.

Ooi JD, Gan PY, Chen T, Eggenhuizen PJ, Chang J, Alikhan MA, Odobasic D, Holdsworth SR, Kitching AR. Ooi JD, et al. Among authors: holdsworth sr. Kidney Int. 2014 Dec;86(6):1140-9. doi: 10.1038/ki.2014.189. Epub 2014 May 28. Kidney Int. 2014. PMID: 24869670 Free article.

7

Mouse models of anti-neutrophil cytoplasmic antibody-associated vasculitis.

Gan PY, Ooi JD, Kitching AR, Holdsworth SR. Gan PY, et al. Among authors: holdsworth sr. Curr Pharm Des. 2015;21(18):2380-90. doi: 10.2174/1381612821666150316121029. Curr Pharm Des. 2015. PMID: 25777754 Review.

8

Myeloperoxidase Peptide-Based Nasal Tolerance in Experimental ANCA-Associated GN.

Gan PY, Tan DS, Ooi JD, Alikhan MA, Kitching AR, Holdsworth SR. Gan PY, et al. Among authors: holdsworth sr. J Am Soc Nephrol. 2016 Feb;27(2):385-91. doi: 10.1681/ASN.2015010089. Epub 2015 Jun 5. J Am Soc Nephrol. 2016. PMID: 26047792 Free PMC article.

9

Mast Cell Stabilization Ameliorates Autoimmune Anti-Myeloperoxidase Glomerulonephritis.

Gan PY, O'Sullivan KM, Ooi JD, Alikhan MA, Odobasic D, Summers SA, Kitching AR, Holdsworth SR. Gan PY, et al. Among authors: holdsworth sr. J Am Soc Nephrol. 2016 May;27(5):1321-33. doi: 10.1681/ASN.2014090906. Epub 2015 Sep 15. J Am Soc Nephrol. 2016. PMID: 26374606 Free PMC article.

10

CD8+ T Cells Effect Glomerular Injury in Experimental Anti-Myeloperoxidase GN.

Chang J, Eggenhuizen P, O'Sullivan KM, Alikhan MA, Holdsworth SR, Ooi JD, Kitching AR. Chang J, et al. Among authors: holdsworth sr. J Am Soc Nephrol. 2017 Jan;28(1):47-55. doi: 10.1681/ASN.2015121356. Epub 2016 Jun 10. J Am Soc Nephrol. 2017. PMID: 27288012 Free PMC article.

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