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Vitamin C-dependent lysine demethylase 6 (KDM6)-mediated demethylation promotes a chromatin state that supports the endothelial-to-hematopoietic transition.
Zhang T, Huang K, Zhu Y, Wang T, Shan Y, Long B, Li Y, Chen Q, Wang P, Zhao S, Li D, Wu C, Kang B, Gu J, Mai Y, Wang Q, Li J, Zhang Y, Liang Z, Guo L, Wu F, Su S, Wang J, Gao M, Zhong X, Liao B, Chen J, Zhang X, Shu X, Pei D, Nie J, Pan G. Zhang T, et al. Among authors: zhang x, zhang y. J Biol Chem. 2019 Sep 13;294(37):13657-13670. doi: 10.1074/jbc.RA119.009757. Epub 2019 Jul 24. J Biol Chem. 2019. PMID: 31341023 Free PMC article.
PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs.
Shan Y, Liang Z, Xing Q, Zhang T, Wang B, Tian S, Huang W, Zhang Y, Yao J, Zhu Y, Huang K, Liu Y, Wang X, Chen Q, Zhang J, Shang B, Li S, Shi X, Liao B, Zhang C, Lai K, Zhong X, Shu X, Wang J, Yao H, Chen J, Pei D, Pan G. Shan Y, et al. Among authors: zhang c, zhang t, zhang j, zhang y. Nat Commun. 2017 Sep 22;8(1):672. doi: 10.1038/s41467-017-00668-4. Nat Commun. 2017. PMID: 28939884 Free PMC article.
BMI1 enables interspecies chimerism with human pluripotent stem cells.
Huang K, Zhu Y, Ma Y, Zhao B, Fan N, Li Y, Song H, Chu S, Ouyang Z, Zhang Q, Xing Q, Lai C, Li N, Zhang T, Gu J, Kang B, Shan Y, Lai K, Huang W, Mai Y, Wang Q, Li J, Lin A, Zhang Y, Zhong X, Liao B, Lai L, Chen J, Pei D, Pan G. Huang K, et al. Among authors: zhang q, zhang t, zhang y. Nat Commun. 2018 Nov 7;9(1):4649. doi: 10.1038/s41467-018-07098-w. Nat Commun. 2018. PMID: 30405129 Free PMC article.
JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells.
Shan Y, Zhang Y, Zhao Y, Wang T, Zhang J, Yao J, Ma N, Liang Z, Huang W, Huang K, Zhang T, Su Z, Chen Q, Zhu Y, Wu C, Zhou T, Sun W, Wei Y, Zhang C, Li C, Su S, Liao B, Zhong M, Zhong X, Nie J, Pei D, Pan G. Shan Y, et al. Among authors: zhang c, zhang t, zhang j, zhang y. Nat Commun. 2020 Jan 20;11(1):382. doi: 10.1038/s41467-019-14028-x. Nat Commun. 2020. PMID: 31959746 Free PMC article.
Characterization and generation of human definitive multipotent hematopoietic stem/progenitor cells.
Zhu Y, Wang T, Gu J, Huang K, Zhang T, Zhang Z, Liu H, Tang J, Mai Y, Zhang Y, Li Y, Feng Y, Kang B, Li J, Shan Y, Chen Q, Zhang J, Long B, Wang J, Gao M, Zhang D, Zhou M, Zhong X, Chen J, Pei D, Nie J, Liu B, Pan G. Zhu Y, et al. Among authors: zhang t, zhang d, zhang z, zhang j, zhang y. Cell Discov. 2020 Dec 1;6(1):89. doi: 10.1038/s41421-020-00213-6. Cell Discov. 2020. PMID: 33298886 Free PMC article.
Coordination of EZH2 and SOX2 specifies human neural fate decision.
Zhao Y, Wang T, Zhang Y, Shi L, Zhang C, Zhang J, Yao J, Chen Q, Zhong X, Wei Y, Shan Y, Pan G. Zhao Y, et al. Among authors: zhang c, zhang j, zhang y. Cell Regen. 2021 Sep 6;10(1):30. doi: 10.1186/s13619-021-00092-6. Cell Regen. 2021. PMID: 34487238 Free PMC article.
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