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Vitamin C-dependent lysine demethylase 6 (KDM6)-mediated demethylation promotes a chromatin state that supports the endothelial-to-hematopoietic transition.
Zhang T, Huang K, Zhu Y, Wang T, Shan Y, Long B, Li Y, Chen Q, Wang P, Zhao S, Li D, Wu C, Kang B, Gu J, Mai Y, Wang Q, Li J, Zhang Y, Liang Z, Guo L, Wu F, Su S, Wang J, Gao M, Zhong X, Liao B, Chen J, Zhang X, Shu X, Pei D, Nie J, Pan G. Zhang T, et al. Among authors: wang j, wang p, wang t, wang q. J Biol Chem. 2019 Sep 13;294(37):13657-13670. doi: 10.1074/jbc.RA119.009757. Epub 2019 Jul 24. J Biol Chem. 2019. PMID: 31341023 Free PMC article.
JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells.
Shan Y, Zhang Y, Zhao Y, Wang T, Zhang J, Yao J, Ma N, Liang Z, Huang W, Huang K, Zhang T, Su Z, Chen Q, Zhu Y, Wu C, Zhou T, Sun W, Wei Y, Zhang C, Li C, Su S, Liao B, Zhong M, Zhong X, Nie J, Pei D, Pan G. Shan Y, et al. Among authors: wang t. Nat Commun. 2020 Jan 20;11(1):382. doi: 10.1038/s41467-019-14028-x. Nat Commun. 2020. PMID: 31959746 Free PMC article.
Characterization and generation of human definitive multipotent hematopoietic stem/progenitor cells.
Zhu Y, Wang T, Gu J, Huang K, Zhang T, Zhang Z, Liu H, Tang J, Mai Y, Zhang Y, Li Y, Feng Y, Kang B, Li J, Shan Y, Chen Q, Zhang J, Long B, Wang J, Gao M, Zhang D, Zhou M, Zhong X, Chen J, Pei D, Nie J, Liu B, Pan G. Zhu Y, et al. Among authors: wang j, wang t. Cell Discov. 2020 Dec 1;6(1):89. doi: 10.1038/s41421-020-00213-6. Cell Discov. 2020. PMID: 33298886 Free PMC article.
Efficient derivation of human trophoblast stem cells from primed pluripotent stem cells.
Wei Y, Wang T, Ma L, Zhang Y, Zhao Y, Lye K, Xiao L, Chen C, Wang Z, Ma Y, Zhou X, Sun F, Li W, Dunk C, Li S, Nagy A, Yu Y, Pan G, Lye SJ, Shan Y. Wei Y, et al. Among authors: wang z, wang t. Sci Adv. 2021 Aug 11;7(33):eabf4416. doi: 10.1126/sciadv.abf4416. Print 2021 Aug. Sci Adv. 2021. PMID: 34380613 Free PMC article.
Coordination of EZH2 and SOX2 specifies human neural fate decision.
Zhao Y, Wang T, Zhang Y, Shi L, Zhang C, Zhang J, Yao J, Chen Q, Zhong X, Wei Y, Shan Y, Pan G. Zhao Y, et al. Among authors: wang t. Cell Regen. 2021 Sep 6;10(1):30. doi: 10.1186/s13619-021-00092-6. Cell Regen. 2021. PMID: 34487238 Free PMC article.
Vitamin C promotes anti-leukemia of DZNep in acute myeloid leukemia.
Long B, Shan Y, Sun Y, Wang T, Li X, Huang K, Zhang W, He Y, Wen R, Li Y, Mai Y, Feng Y, Zhang T, Kang B, Zhang C, Zhu Y, Gu J, Liu J, Zhang X, Pan G. Long B, et al. Among authors: wang t. Biochim Biophys Acta Mol Basis Dis. 2022 May 1;1868(5):166357. doi: 10.1016/j.bbadis.2022.166357. Epub 2022 Feb 7. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 35143932 Free article.
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