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Base Editor Correction of COL7A1 in Recessive Dystrophic Epidermolysis Bullosa Patient-Derived Fibroblasts and iPSCs.
Osborn MJ, Newby GA, McElroy AN, Knipping F, Nielsen SC, Riddle MJ, Xia L, Chen W, Eide CR, Webber BR, Wandall HH, Dabelsteen S, Blazar BR, Liu DR, Tolar J. Osborn MJ, et al. Among authors: newby ga. J Invest Dermatol. 2020 Feb;140(2):338-347.e5. doi: 10.1016/j.jid.2019.07.701. Epub 2019 Aug 19. J Invest Dermatol. 2020. PMID: 31437443 Free PMC article.
Search-and-replace genome editing without double-strand breaks or donor DNA.
Anzalone AV, Randolph PB, Davis JR, Sousa AA, Koblan LW, Levy JM, Chen PJ, Wilson C, Newby GA, Raguram A, Liu DR. Anzalone AV, et al. Among authors: newby ga. Nature. 2019 Dec;576(7785):149-157. doi: 10.1038/s41586-019-1711-4. Epub 2019 Oct 21. Nature. 2019. PMID: 31634902 Free PMC article.
Continuous evolution of SpCas9 variants compatible with non-G PAMs.
Miller SM, Wang T, Randolph PB, Arbab M, Shen MW, Huang TP, Matuszek Z, Newby GA, Rees HA, Liu DR. Miller SM, et al. Among authors: newby ga. Nat Biotechnol. 2020 Apr;38(4):471-481. doi: 10.1038/s41587-020-0412-8. Epub 2020 Feb 10. Nat Biotechnol. 2020. PMID: 32042170 Free PMC article.
72 results