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Effects of microbiota-directed foods in gnotobiotic animals and undernourished children.
Gehrig JL, Venkatesh S, Chang HW, Hibberd MC, Kung VL, Cheng J, Chen RY, Subramanian S, Cowardin CA, Meier MF, O'Donnell D, Talcott M, Spears LD, Semenkovich CF, Henrissat B, Giannone RJ, Hettich RL, Ilkayeva O, Muehlbauer M, Newgard CB, Sawyer C, Head RD, Rodionov DA, Arzamasov AA, Leyn SA, Osterman AL, Hossain MI, Islam M, Choudhury N, Sarker SA, Huq S, Mahmud I, Mostafa I, Mahfuz M, Barratt MJ, Ahmed T, Gordon JI. Gehrig JL, et al. Among authors: chang hw. Science. 2019 Jul 12;365(6449):eaau4732. doi: 10.1126/science.aau4732. Science. 2019. PMID: 31296738 Free PMC article. Clinical Trial.
A sparse covarying unit that describes healthy and impaired human gut microbiota development.
Raman AS, Gehrig JL, Venkatesh S, Chang HW, Hibberd MC, Subramanian S, Kang G, Bessong PO, Lima AAM, Kosek MN, Petri WA Jr, Rodionov DA, Arzamasov AA, Leyn SA, Osterman AL, Huq S, Mostafa I, Islam M, Mahfuz M, Haque R, Ahmed T, Barratt MJ, Gordon JI. Raman AS, et al. Among authors: chang hw. Science. 2019 Jul 12;365(6449):eaau4735. doi: 10.1126/science.aau4735. Science. 2019. PMID: 31296739 Free PMC article.
Gut microbiome contributions to altered metabolism in a pig model of undernutrition.
Chang HW, McNulty NP, Hibberd MC, O'Donnell D, Cheng J, Lombard V, Henrissat B, Ilkayeva O, Muehlbauer MJ, Newgard CB, Barratt MJ, Lin X, Odle J, Gordon JI. Chang HW, et al. Proc Natl Acad Sci U S A. 2021 May 25;118(21):e2024446118. doi: 10.1073/pnas.2024446118. Proc Natl Acad Sci U S A. 2021. PMID: 34001614 Free PMC article.
Prevotella copri-related effects of a therapeutic food for malnutrition.
Chang HW, Lee EM, Wang Y, Zhou C, Pruss KM, Henrissat S, Chen RY, Kao C, Hibberd MC, Lynn HM, Webber DM, Crane M, Cheng J, Rodionov DA, Arzamasov AA, Castillo JJ, Couture G, Chen Y, Balcazo NP Jr, Lebrilla CB, Terrapon N, Henrissat B, Ilkayeva O, Muehlbauer MJ, Newgard CB, Mostafa I, Das S, Mahfuz M, Osterman AL, Barratt MJ, Ahmed T, Gordon JI. Chang HW, et al. bioRxiv [Preprint]. 2023 Dec 20:2023.08.11.553030. doi: 10.1101/2023.08.11.553030. bioRxiv. 2023. Update in: Nat Microbiol. 2024 Apr;9(4):922-937. doi: 10.1038/s41564-024-01628-7 PMID: 37645712 Free PMC article. Updated. Preprint.
Bioactive glycans in a microbiome-directed food for malnourished children.
Hibberd MC, Webber DM, Rodionov DA, Henrissat S, Chen RY, Zhou C, Lynn HM, Wang Y, Chang HW, Lee EM, Lelwala-Guruge J, Kazanov MD, Arzamasov AA, Leyn SA, Lombard V, Terrapon N, Henrissat B, Castillo JJ, Couture G, Bacalzo NP Jr, Chen Y, Lebrilla CB, Mostafa I, Das S, Mahfuz M, Barratt MJ, Osterman AL, Ahmed T, Gordon JI. Hibberd MC, et al. Among authors: chang hw. medRxiv [Preprint]. 2023 Aug 18:2023.08.14.23293998. doi: 10.1101/2023.08.14.23293998. medRxiv. 2023. Update in: Nature. 2024 Jan;625(7993):157-165. doi: 10.1038/s41586-023-06838-3 PMID: 37645824 Free PMC article. Updated. Preprint.
Bioactive glycans in a microbiome-directed food for children with malnutrition.
Hibberd MC, Webber DM, Rodionov DA, Henrissat S, Chen RY, Zhou C, Lynn HM, Wang Y, Chang HW, Lee EM, Lelwala-Guruge J, Kazanov MD, Arzamasov AA, Leyn SA, Lombard V, Terrapon N, Henrissat B, Castillo JJ, Couture G, Bacalzo NP Jr, Chen Y, Lebrilla CB, Mostafa I, Das S, Mahfuz M, Barratt MJ, Osterman AL, Ahmed T, Gordon JI. Hibberd MC, et al. Among authors: chang hw. Nature. 2024 Jan;625(7993):157-165. doi: 10.1038/s41586-023-06838-3. Epub 2023 Dec 13. Nature. 2024. PMID: 38093016 Free PMC article. Clinical Trial.
Prevotella copri and microbiota members mediate the beneficial effects of a therapeutic food for malnutrition.
Chang HW, Lee EM, Wang Y, Zhou C, Pruss KM, Henrissat S, Chen RY, Kao C, Hibberd MC, Lynn HM, Webber DM, Crane M, Cheng J, Rodionov DA, Arzamasov AA, Castillo JJ, Couture G, Chen Y, Balcazo NP Jr, Lebrilla CB, Terrapon N, Henrissat B, Ilkayeva O, Muehlbauer MJ, Newgard CB, Mostafa I, Das S, Mahfuz M, Osterman AL, Barratt MJ, Ahmed T, Gordon JI. Chang HW, et al. Nat Microbiol. 2024 Apr;9(4):922-937. doi: 10.1038/s41564-024-01628-7. Epub 2024 Mar 19. Nat Microbiol. 2024. PMID: 38503977 Free PMC article.
TREM2 deficiency reprograms intestinal macrophages and microbiota to enhance anti-PD-1 tumor immunotherapy.
Di Luccia B, Molgora M, Khantakova D, Jaeger N, Chang HW, Czepielewski RS, Helmink BA, Onufer EJ, Fachi JL, Bhattarai B, Trsan T, Rodrigues PF, Hou J, Bando JK, da Silva CS, Cella M, Gilfillan S, Schreiber RD, Gordon JI, Colonna M. Di Luccia B, et al. Among authors: chang hw. Sci Immunol. 2024 May 17;9(95):eadi5374. doi: 10.1126/sciimmunol.adi5374. Epub 2024 May 17. Sci Immunol. 2024. PMID: 38758808 Free PMC article.
1,566 results