Cheng QJ - Search Results

1

An NFκB Activity Calculator to Delineate Signaling Crosstalk: Type I and II Interferons Enhance NFκB via Distinct Mechanisms.

Mitchell S, Mercado EL, Adelaja A, Ho JQ, Cheng QJ, Ghosh G, Hoffmann A. Mitchell S, et al. Among authors: cheng qj. Front Immunol. 2019 Jun 25;10:1425. doi: 10.3389/fimmu.2019.01425. eCollection 2019. Front Immunol. 2019. PMID: 31293585 Free PMC article.

2

Sequential conditioning-stimulation reveals distinct gene- and stimulus-specific effects of Type I and II IFN on human macrophage functions.

Cheng Q, Behzadi F, Sen S, Ohta S, Spreafico R, Teles R, Modlin RL, Hoffmann A. Cheng Q, et al. Sci Rep. 2019 Mar 27;9(1):5288. doi: 10.1038/s41598-019-40503-y. Sci Rep. 2019. PMID: 30918279 Free PMC article.

3

High Dose IFN-β Activates GAF to Enhance Expression of ISGF3 Target Genes in MLE12 Epithelial Cells.

Kishimoto K, Wilder CL, Buchanan J, Nguyen M, Okeke C, Hoffmann A, Cheng QJ. Kishimoto K, et al. Among authors: cheng qj. Front Immunol. 2021 Apr 9;12:651254. doi: 10.3389/fimmu.2021.651254. eCollection 2021. Front Immunol. 2021. PMID: 33897699 Free PMC article.

4

NF-κB dynamics determine the stimulus specificity of epigenomic reprogramming in macrophages.

Cheng QJ, Ohta S, Sheu KM, Spreafico R, Adelaja A, Taylor B, Hoffmann A. Cheng QJ, et al. Science. 2021 Jun 18;372(6548):1349-1353. doi: 10.1126/science.abc0269. Science. 2021. PMID: 34140389 Free PMC article.

5

Stochastic models of nucleosome dynamics reveal regulatory rules of stimulus-induced epigenome remodeling.

Kim J, Sheu KM, Cheng QJ, Hoffmann A, Enciso G. Kim J, et al. Among authors: cheng qj. Cell Rep. 2022 Jul 12;40(2):111076. doi: 10.1016/j.celrep.2022.111076. Cell Rep. 2022. PMID: 35830792 Free PMC article.

6

A stimulus-contingent positive feedback loop enables IFN-β dose-dependent activation of pro-inflammatory genes.

Wilder CL, Lefaudeux D, Mathenge R, Kishimoto K, Zuniga Munoz A, Nguyen MA, Meyer AS, Cheng QJ, Hoffmann A. Wilder CL, et al. Among authors: cheng qj. Mol Syst Biol. 2023 May 9;19(5):e11294. doi: 10.15252/msb.202211294. Epub 2023 Mar 17. Mol Syst Biol. 2023. PMID: 36929731 Free PMC article.

7

Tonic TNF conditioning of macrophages safeguards stimulus-specific inflammatory responses.

Luecke S, Adelaja A, Guo X, Sen S, Spreafico R, Singh A, Liu Y, Taylor B, Diaz J, Cheng Q, Hoffmann A. Luecke S, et al. EMBO Rep. 2023 Jul 5;24(7):e55986. doi: 10.15252/embr.202255986. Epub 2023 May 22. EMBO Rep. 2023. PMID: 37212045 Free PMC article.

8

IRF1 cooperates with ISGF3 or GAF to form innate immune de novo enhancers in macrophages.

Chavez C, Lin K, Malveaux A, Gorin A, Brizuela S, Cheng QJ, Hoffmann A. Chavez C, et al. Among authors: cheng qj. Sci Signal. 2025 Jan 7;18(868):eado8860. doi: 10.1126/scisignal.ado8860. Epub 2025 Jan 7. Sci Signal. 2025. PMID: 39772531

9

Dectin-1 ligands produce distinct training phenotypes in human monocytes through differential activation of signaling networks.

Cheng QJ, Farrell K, Fenn J, Ma Z, Makanani SK, Siemsen J. Cheng QJ, et al. Sci Rep. 2024 Jan 17;14(1):1454. doi: 10.1038/s41598-024-51620-8. Sci Rep. 2024. PMID: 38228717 Free PMC article.

10

GM-CSF receptor expression determines opposing innate memory phenotypes at different stages of myelopoiesis.

Guerrero P, Bono C, Sobén M, Guiu A, Cheng QJ, Gil ML, Yáñez A. Guerrero P, et al. Among authors: cheng qj. Blood. 2024 Jun 27;143(26):2763-2777. doi: 10.1182/blood.2024024330. Blood. 2024. PMID: 38603633

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