van Dinther M - Search Results

1

VprBP mitigates TGF-β and Activin signaling by promoting Smurf1-mediated type I receptor degradation.

Li Y, Cui C, Xie F, Kiełbasa S, Mei H, van Dinther M, van Dam H, Bauer A, Zhang L, Ten Dijke P. Li Y, et al. Among authors: van dinther m, van dam h. J Mol Cell Biol. 2020 Feb 20;12(2):138-151. doi: 10.1093/jmcb/mjz057. J Mol Cell Biol. 2020. PMID: 31291647 Free PMC article.

2

RLP, a novel Ras-like protein, is an immediate-early transforming growth factor-beta (TGF-beta) target gene that negatively regulates transcriptional activity induced by TGF-beta.

Piek E, Van Dinther M, Parks WT, Sallee JM, Böttinger EP, Roberts AB, Ten Dijke P. Piek E, et al. Among authors: van dinther m. Biochem J. 2004 Oct 1;383(Pt 1):187-99. doi: 10.1042/BJ20040774. Biochem J. 2004. PMID: 15239668 Free PMC article.

3

The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells.

Deckers M, van Dinther M, Buijs J, Que I, Löwik C, van der Pluijm G, ten Dijke P. Deckers M, et al. Among authors: van der pluijm g, van dinther m. Cancer Res. 2006 Feb 15;66(4):2202-9. doi: 10.1158/0008-5472.CAN-05-3560. Cancer Res. 2006. PMID: 16489022

4

BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis.

Scharpfenecker M, van Dinther M, Liu Z, van Bezooijen RL, Zhao Q, Pukac L, Löwik CW, ten Dijke P. Scharpfenecker M, et al. Among authors: van dinther m, van bezooijen rl. J Cell Sci. 2007 Mar 15;120(Pt 6):964-72. doi: 10.1242/jcs.002949. Epub 2007 Feb 20. J Cell Sci. 2007. PMID: 17311849

5

Oral administration of GW788388, an inhibitor of TGF-beta type I and II receptor kinases, decreases renal fibrosis.

Petersen M, Thorikay M, Deckers M, van Dinther M, Grygielko ET, Gellibert F, de Gouville AC, Huet S, ten Dijke P, Laping NJ. Petersen M, et al. Among authors: van dinther m. Kidney Int. 2008 Mar;73(6):705-15. doi: 10.1038/sj.ki.5002717. Epub 2007 Dec 12. Kidney Int. 2008. PMID: 18075500 Free article.

6

Two novel type II receptors mediate BMP signalling and are required to establish left-right asymmetry in zebrafish.

Monteiro R, van Dinther M, Bakkers J, Wilkinson R, Patient R, ten Dijke P, Mummery C. Monteiro R, et al. Among authors: van dinther m. Dev Biol. 2008 Mar 1;315(1):55-71. doi: 10.1016/j.ydbio.2007.11.038. Epub 2007 Dec 15. Dev Biol. 2008. PMID: 18222420 Free article.

7

Dominant-negative ALK2 allele associates with congenital heart defects.

Smith KA, Joziasse IC, Chocron S, van Dinther M, Guryev V, Verhoeven MC, Rehmann H, van der Smagt JJ, Doevendans PA, Cuppen E, Mulder BJ, Ten Dijke P, Bakkers J. Smith KA, et al. Among authors: van der smagt jj, van dinther m. Circulation. 2009 Jun 23;119(24):3062-9. doi: 10.1161/CIRCULATIONAHA.108.843714. Epub 2009 Jun 8. Circulation. 2009. PMID: 19506109

8

Smad3 is a key nonredundant mediator of transforming growth factor beta signaling in Nme mouse mammary epithelial cells.

Dzwonek J, Preobrazhenska O, Cazzola S, Conidi A, Schellens A, van Dinther M, Stubbs A, Klippel A, Huylebroeck D, ten Dijke P, Verschueren K. Dzwonek J, et al. Among authors: van dinther m. Mol Cancer Res. 2009 Aug;7(8):1342-53. doi: 10.1158/1541-7786.MCR-08-0558. Epub 2009 Aug 11. Mol Cancer Res. 2009. PMID: 19671686

9

VEGF and inhibitors of TGFbeta type-I receptor kinase synergistically promote blood-vessel formation by inducing alpha5-integrin expression.

Liu Z, Kobayashi K, van Dinther M, van Heiningen SH, Valdimarsdottir G, van Laar T, Scharpfenecker M, Löwik CW, Goumans MJ, Ten Dijke P, Pardali E. Liu Z, et al. Among authors: van laar t, van dinther m, van heiningen sh. J Cell Sci. 2009 Sep 15;122(Pt 18):3294-302. doi: 10.1242/jcs.048942. Epub 2009 Aug 25. J Cell Sci. 2009. PMID: 19706683

10

ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formation.

van Dinther M, Visser N, de Gorter DJ, Doorn J, Goumans MJ, de Boer J, ten Dijke P. van Dinther M, et al. J Bone Miner Res. 2010 Jun;25(6):1208-15. doi: 10.1359/jbmr.091110. J Bone Miner Res. 2010. PMID: 19929436 Free article.

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