Izumi-Nakaseko H - Search Results

1

Dasatinib can Impair Left Ventricular Mechanical Function But May Lack Proarrhythmic Effect: A Proposal of Non-clinical Guidance for Predicting Clinical Cardiovascular Adverse Events of Tyrosine Kinase Inhibitors.

Izumi-Nakaseko H, Fujiyoshi M, Hagiwara-Nagasawa M, Goto A, Chiba K, Kambayashi R, Naito AT, Ando K, Kanda Y, Ishii I, Sugiyama A. Izumi-Nakaseko H, et al. Cardiovasc Toxicol. 2020 Feb;20(1):58-70. doi: 10.1007/s12012-019-09538-5. Cardiovasc Toxicol. 2020. PMID: 31280457

2

Disruption of Stard10 gene alters the PPARα-mediated bile acid homeostasis.

Ito M, Yamanashi Y, Toyoda Y, Izumi-Nakaseko H, Oda S, Sugiyama A, Kuroda M, Suzuki H, Takada T, Adachi-Akahane S. Ito M, et al. Biochim Biophys Acta. 2013 Feb;1831(2):459-68. doi: 10.1016/j.bbalip.2012.11.008. Epub 2012 Nov 28. Biochim Biophys Acta. 2013. PMID: 23200860

3

Effects of selective IKr channel blockade by E-4031 on ventricular electro-mechanical relationship in the halothane-anesthetized dogs.

Izumi-Nakaseko H, Nakamura Y, Cao X, Ohara H, Yamazaki Y, Ueda N, Ando K, Sugiyama A. Izumi-Nakaseko H, et al. Eur J Pharmacol. 2014 Oct 5;740:263-70. doi: 10.1016/j.ejphar.2014.06.064. Epub 2014 Jul 17. Eur J Pharmacol. 2014. PMID: 25038475

4

Analysis of Onset Mechanisms of a Sphingosine 1-Phosphate Receptor Modulator Fingolimod-Induced Atrioventricular Conduction Block and QT-Interval Prolongation.

Yagi Y, Nakamura Y, Kitahara K, Harada T, Kato K, Ninomiya T, Cao X, Ohara H, Izumi-Nakaseko H, Suzuki K, Ando K, Sugiyama A. Yagi Y, et al. Toxicol Appl Pharmacol. 2014 Nov 15;281(1):39-47. doi: 10.1016/j.taap.2014.09.006. Epub 2014 Sep 16. Toxicol Appl Pharmacol. 2014. PMID: 25223691

5

Azithromycin Can Prolong QT Interval and Suppress Ventricular Contraction, but Will Not Induce Torsade de Pointes.

Ohara H, Nakamura Y, Watanabe Y, Cao X, Yamazaki Y, Izumi-Nakaseko H, Ando K, Yamazaki H, Yamazaki J, Ikeda T, Sugiyama A. Ohara H, et al. Cardiovasc Toxicol. 2015 Jul;15(3):232-40. doi: 10.1007/s12012-014-9289-4. Cardiovasc Toxicol. 2015. PMID: 25367413

6

Intravenous Administration of Apomorphine Does NOT Induce Long QT Syndrome: Experimental Evidence from In Vivo Canine Models.

Watanabe Y, Nakamura Y, Cao X, Ohara H, Yamazaki Y, Murayama N, Sugiyama Y, Izumi-Nakaseko H, Ando K, Yamazaki H, Sugiyama A. Watanabe Y, et al. Basic Clin Pharmacol Toxicol. 2015 Jun;116(6):468-75. doi: 10.1111/bcpt.12343. Epub 2014 Nov 22. Basic Clin Pharmacol Toxicol. 2015. PMID: 25370785 Free article.

7

Fluvoxamine by itself has potential to directly induce long QT syndrome at supra-therapeutic concentrations.

Yamazaki-Hashimoto Y, Nakamura Y, Ohara H, Cao X, Kitahara K, Izumi-Nakaseko H, Ando K, Yamazaki H, Ikeda T, Yamazaki J, Sugiyama A. Yamazaki-Hashimoto Y, et al. J Toxicol Sci. 2015 Feb;40(1):33-42. doi: 10.2131/jts.40.33. J Toxicol Sci. 2015. PMID: 25560394 Free article.

8

Why Can dl-Sotalol Prolong the QT Interval In Vivo Despite Its Weak Inhibitory Effect on hERG K(+) Channels In Vitro? Electrophysiological and Pharmacokinetic Analysis with the Halothane-Anesthetized Guinea Pig Model.

Katagi J, Nakamura Y, Cao X, Ohara H, Honda A, Izumi-Nakaseko H, Ando K, Sugiyama A. Katagi J, et al. Cardiovasc Toxicol. 2016 Apr;16(2):138-46. doi: 10.1007/s12012-015-9322-2. Cardiovasc Toxicol. 2016. PMID: 25822712

9

Possible effects of inhibition of IKr and IKs on field-potential waveforms in the human iPS cell-derived cardiomyocytes sheet.

Matsuo J, Nakamura Y, Izumi-Nakaseko H, Ando K, Sekino Y, Sugiyama A. Matsuo J, et al. J Pharmacol Sci. 2015 Jun;128(2):92-5. doi: 10.1016/j.jphs.2015.05.004. Epub 2015 May 23. J Pharmacol Sci. 2015. PMID: 26072297 Free article.

10

Cardiohemodynamic and electrophysiological effects of a selective EP4 receptor agonist ONO--AE1--329 in the halothane-anesthetized dogs.

Nomura H, Nakamura Y, Cao X, Honda A, Katagi J, Ohara H, Izumi-Nakaseko H, Satoh Y, Ando K, Sugiyama A. Nomura H, et al. Eur J Pharmacol. 2015 Aug 15;761:217-25. doi: 10.1016/j.ejphar.2015.06.012. Epub 2015 Jun 11. Eur J Pharmacol. 2015. PMID: 26073024

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