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ALDH2 deficiency promotes alcohol-associated liver cancer by activating oncogenic pathways via oxidized DNA-enriched extracellular vesicles.
Seo W, Gao Y, He Y, Sun J, Xu H, Feng D, Park SH, Cho YE, Guillot A, Ren T, Wu R, Wang J, Kim SJ, Hwang S, Liangpunsakul S, Yang Y, Niu J, Gao B. Seo W, et al. Among authors: kim sj. J Hepatol. 2019 Nov;71(5):1000-1011. doi: 10.1016/j.jhep.2019.06.018. Epub 2019 Jul 4. J Hepatol. 2019. PMID: 31279903 Free PMC article.
Alcohol inhibits T-cell glucose metabolism and hepatitis in ALDH2-deficient mice and humans: roles of acetaldehyde and glucocorticoids.
Gao Y, Zhou Z, Ren T, Kim SJ, He Y, Seo W, Guillot A, Ding Y, Wu R, Shao S, Wang X, Zhang H, Wang W, Feng D, Xu M, Han E, Zhong W, Zhou Z, Pacher P, Niu J, Gao B. Gao Y, et al. Among authors: kim sj. Gut. 2019 Jul;68(7):1311-1322. doi: 10.1136/gutjnl-2018-316221. Epub 2018 Aug 18. Gut. 2019. PMID: 30121625 Free PMC article.
Obesity in acute alcoholic hepatitis increases morbidity and mortality.
Parker R, Kim SJ, Im GY, Nahas J, Dhesi B, Vergis N, Sinha A, Ghezzi A, Rink MR, McCune A, Aithal GP, Newsome PN, Weston CJ, Holt A, Gao B. Parker R, et al. Among authors: kim sj. EBioMedicine. 2019 Jul;45:511-518. doi: 10.1016/j.ebiom.2019.03.046. Epub 2019 Jul 3. EBioMedicine. 2019. PMID: 31278069 Free PMC article.
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