Sen NE - Search Results

1

SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes.

Auburger G, Gispert S, Torres-Odio S, Jendrach M, Brehm N, Canet-Pons J, Key J, Sen NE. Auburger G, et al. Among authors: sen ne. Int J Mol Sci. 2019 Jul 4;20(13):3284. doi: 10.3390/ijms20133284. Int J Mol Sci. 2019. PMID: 31277379 Free PMC article.

2

Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated.

Halbach MV, Stehning T, Damrath E, Jendrach M, Şen NE, Başak AN, Auburger G. Halbach MV, et al. Among authors: sen ne. PLoS One. 2015 Mar 19;10(3):e0121089. doi: 10.1371/journal.pone.0121089. eCollection 2015. PLoS One. 2015. PMID: 25790475 Free PMC article.

3

Ataxin-2 (Atxn2)-Knock-Out Mice Show Branched Chain Amino Acids and Fatty Acids Pathway Alterations.

Meierhofer D, Halbach M, Şen NE, Gispert S, Auburger G. Meierhofer D, et al. Among authors: sen ne. Mol Cell Proteomics. 2016 May;15(5):1728-39. doi: 10.1074/mcp.M115.056770. Epub 2016 Feb 5. Mol Cell Proteomics. 2016. PMID: 26850065 Free PMC article.

4

Search for SCA2 blood RNA biomarkers highlights Ataxin-2 as strong modifier of the mitochondrial factor PINK1 levels.

Sen NE, Drost J, Gispert S, Torres-Odio S, Damrath E, Klinkenberg M, Hamzeiy H, Akdal G, Güllüoğlu H, Başak AN, Auburger G. Sen NE, et al. Neurobiol Dis. 2016 Dec;96:115-126. doi: 10.1016/j.nbd.2016.09.002. Epub 2016 Sep 3. Neurobiol Dis. 2016. PMID: 27597528

5

Quantitative Global Proteomics of Yeast PBP1 Deletion Mutants and Their Stress Responses Identifies Glucose Metabolism, Mitochondrial, and Stress Granule Changes.

Seidel G, Meierhofer D, Şen NE, Guenther A, Krobitsch S, Auburger G. Seidel G, et al. Among authors: sen ne. J Proteome Res. 2017 Feb 3;16(2):504-515. doi: 10.1021/acs.jproteome.6b00647. Epub 2016 Dec 22. J Proteome Res. 2017. PMID: 27966978

6

Efficient Prevention of Neurodegenerative Diseases by Depletion of Starvation Response Factor Ataxin-2.

Auburger G, Sen NE, Meierhofer D, Başak AN, Gitler AD. Auburger G, et al. Among authors: sen ne. Trends Neurosci. 2017 Aug;40(8):507-516. doi: 10.1016/j.tins.2017.06.004. Epub 2017 Jul 3. Trends Neurosci. 2017. PMID: 28684172 Review.

7

Generation of an Atxn2-CAG100 knock-in mouse reveals N-acetylaspartate production deficit due to early Nat8l dysregulation.

Sen NE, Canet-Pons J, Halbach MV, Arsovic A, Pilatus U, Chae WH, Kaya ZE, Seidel K, Rollmann E, Mittelbronn M, Meierhofer D, De Zeeuw CI, Bosman LWJ, Gispert S, Auburger G. Sen NE, et al. Neurobiol Dis. 2019 Dec;132:104559. doi: 10.1016/j.nbd.2019.104559. Epub 2019 Jul 31. Neurobiol Dis. 2019. PMID: 31376479 Free article.

8

In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism.

Sen NE, Arsovic A, Meierhofer D, Brodesser S, Oberschmidt C, Canet-Pons J, Kaya ZE, Halbach MV, Gispert S, Sandhoff K, Auburger G. Sen NE, et al. Int J Mol Sci. 2019 Nov 21;20(23):5854. doi: 10.3390/ijms20235854. Int J Mol Sci. 2019. PMID: 31766565 Free PMC article.

9

Mid-Gestation lethality of Atxn2l-Ablated Mice.

Key J, Harter PN, Sen NE, Gradhand E, Auburger G, Gispert S. Key J, et al. Among authors: sen ne. Int J Mol Sci. 2020 Jul 20;21(14):5124. doi: 10.3390/ijms21145124. Int J Mol Sci. 2020. PMID: 32698485 Free PMC article.

10

Mouse Ataxin-2 Expansion Downregulates CamKII and Other Calcium Signaling Factors, Impairing Granule-Purkinje Neuron Synaptic Strength.

Arsović A, Halbach MV, Canet-Pons J, Esen-Sehir D, Döring C, Freudenberg F, Czechowska N, Seidel K, Baader SL, Gispert S, Sen NE, Auburger G. Arsović A, et al. Among authors: sen ne. Int J Mol Sci. 2020 Sep 12;21(18):6673. doi: 10.3390/ijms21186673. Int J Mol Sci. 2020. PMID: 32932600 Free PMC article.

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