Ashford MB - Search Results

1

Evaluating liver uptake and distribution of different poly(2-methyl-2-oxazoline) modified lysine dendrimers following intravenous administration.

England RM, Moss JI, Hill KJ, Elvevold K, Smedsrød B, Ashford MB. England RM, et al. Among authors: ashford mb. Biomater Sci. 2019 Aug 1;7(8):3418-3424. doi: 10.1039/c9bm00385a. Epub 2019 Jul 3. Biomater Sci. 2019. PMID: 31268069

2

Tumour regression and improved gastrointestinal tolerability from controlled release of SN-38 from novel polyoxazoline-modified dendrimers.

England RM, Hare JI, Barnes J, Wilson J, Smith A, Strittmatter N, Kemmitt PD, Waring MJ, Barry ST, Alexander C, Ashford MB. England RM, et al. Among authors: ashford mb. J Control Release. 2017 Feb 10;247:73-85. doi: 10.1016/j.jconrel.2016.12.034. Epub 2016 Dec 30. J Control Release. 2017. PMID: 28043863 Free article.

3

Nanomanufacturing through microfluidic-assisted nanoprecipitation: Advanced analytics and structure-activity relationships.

Donno R, Gennari A, Lallana E, De La Rosa JMR, d'Arcy R, Treacher K, Hill K, Ashford M, Tirelli N. Donno R, et al. Int J Pharm. 2017 Dec 20;534(1-2):97-107. doi: 10.1016/j.ijpharm.2017.10.006. Epub 2017 Oct 7. Int J Pharm. 2017. PMID: 29017804

4

Endocytic Profiling of Cancer Cell Models Reveals Critical Factors Influencing LNP-Mediated mRNA Delivery and Protein Expression.

Sayers EJ, Peel SE, Schantz A, England RM, Beano M, Bates SM, Desai AS, Puri S, Ashford MB, Jones AT. Sayers EJ, et al. Among authors: ashford mb. Mol Ther. 2019 Nov 6;27(11):1950-1962. doi: 10.1016/j.ymthe.2019.07.018. Epub 2019 Aug 5. Mol Ther. 2019. PMID: 31427168 Free PMC article.

5

High-resolution 3D visualization of nanomedicine distribution in tumors.

Moss JI, Barjat H, Emmas SA, Strittmatter N, Maynard J, Goodwin RJA, Storm G, Lammers T, Puri S, Ashford MB, Barry ST. Moss JI, et al. Among authors: ashford mb. Theranostics. 2020 Jan 1;10(2):880-897. doi: 10.7150/thno.37178. eCollection 2020. Theranostics. 2020. PMID: 31903157 Free PMC article.

6

Synthesis and Characterization of Dendrimer-Based Polysarcosine Star Polymers: Well-Defined, Versatile Platforms Designed for Drug-Delivery Applications.

England RM, Moss JI, Gunnarsson A, Parker JS, Ashford MB. England RM, et al. Among authors: ashford mb. Biomacromolecules. 2020 Aug 10;21(8):3332-3341. doi: 10.1021/acs.biomac.0c00768. Epub 2020 Jul 28. Biomacromolecules. 2020. PMID: 32672451

7

Design and optimisation of dendrimer-conjugated Bcl-2/x_L inhibitor, AZD0466, with improved therapeutic index for cancer therapy.

Patterson CM, Balachander SB, Grant I, Pop-Damkov P, Kelly B, McCoull W, Parker J, Giannis M, Hill KJ, Gibbons FD, Hennessy EJ, Kemmitt P, Harmer AR, Gales S, Purbrick S, Redmond S, Skinner M, Graham L, Secrist JP, Schuller AG, Wen S, Adam A, Reimer C, Cidado J, Wild M, Gangl E, Fawell SE, Saeh J, Davies BR, Owen DJ, Ashford MB. Patterson CM, et al. Among authors: ashford mb. Commun Biol. 2021 Jan 25;4(1):112. doi: 10.1038/s42003-020-01631-8. Commun Biol. 2021. PMID: 33495510 Free PMC article.

8

Method to Investigate the Distribution of Water-Soluble Drug-Delivery Systems in Fresh Frozen Tissues Using Imaging Mass Cytometry.

Strittmatter N, England RM, Race AM, Sutton D, Moss JI, Maglennon G, Ling S, Wong E, Rose J, Purvis I, Macdonald R, Barry ST, Ashford MB, Goodwin RJA. Strittmatter N, et al. Among authors: ashford mb. Anal Chem. 2021 Mar 2;93(8):3742-3749. doi: 10.1021/acs.analchem.0c03908. Epub 2021 Feb 19. Anal Chem. 2021. PMID: 33606520

9

Multi-modal molecular imaging maps the correlation between tumor microenvironments and nanomedicine distribution.

Strittmatter N, Moss JI, Race AM, Sutton D, Canales JR, Ling S, Wong E, Wilson J, Smith A, Howes C, Bunch J, Barry ST, Goodwin RJA, Ashford MB. Strittmatter N, et al. Among authors: ashford mb. Theranostics. 2022 Feb 14;12(5):2162-2174. doi: 10.7150/thno.68000. eCollection 2022. Theranostics. 2022. PMID: 35265205 Free PMC article.

10

Synthesis, characterisation and evaluation of hyperbranched N-(2-hydroxypropyl) methacrylamides for transport and delivery in pancreatic cell lines in vitro and in vivo.

Anane-Adjei AB, Fletcher NL, Cavanagh RJ, Houston ZH, Crawford T, Pearce AK, Taresco V, Ritchie AA, Clarke P, Grabowska AM, Gellert PR, Ashford MB, Kellam B, Thurecht KJ, Alexander C. Anane-Adjei AB, et al. Among authors: ashford mb. Biomater Sci. 2022 May 4;10(9):2328-2344. doi: 10.1039/d1bm01548f. Biomater Sci. 2022. PMID: 35380131

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