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Tau pathology reduction with SM07883, a novel, potent, and selective oral DYRK1A inhibitor: A potential therapeutic for Alzheimer's disease.
Melchior B, Mittapalli GK, Lai C, Duong-Polk K, Stewart J, Güner B, Hofilena B, Tjitro A, Anderson SD, Herman DS, Dellamary L, Swearingen CJ, Sunil KC, Yazici Y. Melchior B, et al. Among authors: stewart j. Aging Cell. 2019 Oct;18(5):e13000. doi: 10.1111/acel.13000. Epub 2019 Jul 3. Aging Cell. 2019. PMID: 31267651 Free PMC article.
The CLK inhibitor SM08502 induces anti-tumor activity and reduces Wnt pathway gene expression in gastrointestinal cancer models.
Tam BY, Chiu K, Chung H, Bossard C, Nguyen JD, Creger E, Eastman BW, Mak CC, Ibanez M, Ghias A, Cahiwat J, Do L, Cho S, Nguyen J, Deshmukh V, Stewart J, Chen CW, Barroga C, Dellamary L, Kc SK, Phalen TJ, Hood J, Cha S, Yazici Y. Tam BY, et al. Among authors: stewart j. Cancer Lett. 2020 Mar 31;473:186-197. doi: 10.1016/j.canlet.2019.09.009. Epub 2019 Sep 24. Cancer Lett. 2020. PMID: 31560935 Free article.
A small-molecule inhibitor of the Wnt pathway (SM04690) as a potential disease modifying agent for the treatment of osteoarthritis of the knee.
Deshmukh V, Hu H, Barroga C, Bossard C, Kc S, Dellamary L, Stewart J, Chiu K, Ibanez M, Pedraza M, Seo T, Do L, Cho S, Cahiwat J, Tam B, Tambiah JRS, Hood J, Lane NE, Yazici Y. Deshmukh V, et al. Among authors: stewart j. Osteoarthritis Cartilage. 2018 Jan;26(1):18-27. doi: 10.1016/j.joca.2017.08.015. Epub 2017 Sep 6. Osteoarthritis Cartilage. 2018. PMID: 28888902 Free article.
Delayed onset of ocean acidification in the Gulf of Maine.
Stewart JA, Williams B, LaVigne M, Wanamaker AD, Strong AL, Jellison B, Whitney NM, Thatcher DL, Robinson LF, Halfar J, Adey W. Stewart JA, et al. Sci Rep. 2025 Jan 15;15(1):2039. doi: 10.1038/s41598-024-84537-3. Sci Rep. 2025. PMID: 39814808 Free PMC article.
Modular DNA origami-based electrochemical detection of DNA and proteins.
Jeon BJ, Guareschi MM, Stewart JM, Wu E, Gopinath A, Arroyo-Currás N, Dauphin-Ducharme P, Plaxco KW, Lukeman PS, Rothemund PWK. Jeon BJ, et al. Among authors: stewart jm. Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2311279121. doi: 10.1073/pnas.2311279121. Epub 2024 Dec 30. Proc Natl Acad Sci U S A. 2025. PMID: 39793064
7,440 results