Koumenis C - Search Results

1

ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression.

Tameire F, Verginadis II, Leli NM, Polte C, Conn CS, Ojha R, Salas Salinas C, Chinga F, Monroy AM, Fu W, Wang P, Kossenkov A, Ye J, Amaravadi RK, Ignatova Z, Fuchs SY, Diehl JA, Ruggero D, Koumenis C. Tameire F, et al. Among authors: koumenis c. Nat Cell Biol. 2019 Jul;21(7):889-899. doi: 10.1038/s41556-019-0347-9. Epub 2019 Jul 1. Nat Cell Biol. 2019. PMID: 31263264 Free PMC article.

2

The PERK/eIF2alpha/ATF4 module of the UPR in hypoxia resistance and tumor growth.

Fels DR, Koumenis C. Fels DR, et al. Among authors: koumenis c. Cancer Biol Ther. 2006 Jul;5(7):723-8. doi: 10.4161/cbt.5.7.2967. Epub 2006 Jul 1. Cancer Biol Ther. 2006. PMID: 16861899 Free article. Review.

3

Hypoxia and the unfolded protein response.

Koumenis C, Bi M, Ye J, Feldman D, Koong AC. Koumenis C, et al. Methods Enzymol. 2007;435:275-93. doi: 10.1016/S0076-6879(07)35014-3. Methods Enzymol. 2007. PMID: 17998059

4

Preferential cytotoxicity of bortezomib toward hypoxic tumor cells via overactivation of endoplasmic reticulum stress pathways.

Fels DR, Ye J, Segan AT, Kridel SJ, Spiotto M, Olson M, Koong AC, Koumenis C. Fels DR, et al. Among authors: koumenis c. Cancer Res. 2008 Nov 15;68(22):9323-30. doi: 10.1158/0008-5472.CAN-08-2873. Cancer Res. 2008. PMID: 19010906 Free PMC article.

5

ATF4, an ER stress and hypoxia-inducible transcription factor and its potential role in hypoxia tolerance and tumorigenesis.

Ye J, Koumenis C. Ye J, et al. Among authors: koumenis c. Curr Mol Med. 2009 May;9(4):411-6. doi: 10.2174/156652409788167096. Curr Mol Med. 2009. PMID: 19519398 Review.

6

Inducible priming phosphorylation promotes ligand-independent degradation of the IFNAR1 chain of type I interferon receptor.

Bhattacharya S, HuangFu WC, Liu J, Veeranki S, Baker DP, Koumenis C, Diehl JA, Fuchs SY. Bhattacharya S, et al. Among authors: koumenis c. J Biol Chem. 2010 Jan 22;285(4):2318-25. doi: 10.1074/jbc.M109.071498. Epub 2009 Nov 30. J Biol Chem. 2010. PMID: 19948722 Free PMC article.

7

The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation.

Ye J, Kumanova M, Hart LS, Sloane K, Zhang H, De Panis DN, Bobrovnikova-Marjon E, Diehl JA, Ron D, Koumenis C. Ye J, et al. Among authors: koumenis c. EMBO J. 2010 Jun 16;29(12):2082-96. doi: 10.1038/emboj.2010.81. Epub 2010 May 14. EMBO J. 2010. PMID: 20473272 Free PMC article.

8

Role of p38 protein kinase in the ligand-independent ubiquitination and down-regulation of the IFNAR1 chain of type I interferon receptor.

Bhattacharya S, Qian J, Tzimas C, Baker DP, Koumenis C, Diehl JA, Fuchs SY. Bhattacharya S, et al. Among authors: koumenis c. J Biol Chem. 2011 Jun 24;286(25):22069-76. doi: 10.1074/jbc.M111.238766. Epub 2011 May 3. J Biol Chem. 2011. PMID: 21540188 Free PMC article.

9

Modulation of CCAAT/enhancer binding protein homologous protein (CHOP)-dependent DR5 expression by nelfinavir sensitizes glioblastoma multiforme cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).

Tian X, Ye J, Alonso-Basanta M, Hahn SM, Koumenis C, Dorsey JF. Tian X, et al. Among authors: koumenis c. J Biol Chem. 2011 Aug 19;286(33):29408-29416. doi: 10.1074/jbc.M110.197665. Epub 2011 Jun 22. J Biol Chem. 2011. PMID: 21697087 Free PMC article.

10

Dual PI3K/mTOR inhibitor NVP-BEZ235 suppresses hypoxia-inducible factor (HIF)-1α expression by blocking protein translation and increases cell death under hypoxia.

Karar J, Cerniglia GJ, Lindsten T, Koumenis C, Maity A. Karar J, et al. Among authors: koumenis c. Cancer Biol Ther. 2012 Sep;13(11):1102-11. doi: 10.4161/cbt.21144. Epub 2012 Aug 16. Cancer Biol Ther. 2012. PMID: 22895065 Free PMC article.

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