Welc SS - Search Results

1

Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy.

Welc SS, Flores I, Wehling-Henricks M, Ramos J, Wang Y, Bertoni C, Tidball JG. Welc SS, et al. Nat Commun. 2019 Jun 26;10(1):2788. doi: 10.1038/s41467-019-10614-1. Nat Commun. 2019. PMID: 31243277 Free PMC article.

2

Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy.

Wehling-Henricks M, Li Z, Lindsey C, Wang Y, Welc SS, Ramos JN, Khanlou N, Kuro-O M, Tidball JG. Wehling-Henricks M, et al. Among authors: welc ss. Hum Mol Genet. 2016 Jun 15;25(12):2465-2482. doi: 10.1093/hmg/ddw111. Epub 2016 May 6. Hum Mol Genet. 2016. PMID: 27154199 Free PMC article.

3

Macrophages escape Klotho gene silencing in the mdx mouse model of Duchenne muscular dystrophy and promote muscle growth and increase satellite cell numbers through a Klotho-mediated pathway.

Wehling-Henricks M, Welc SS, Samengo G, Rinaldi C, Lindsey C, Wang Y, Lee J, Kuro-O M, Tidball JG. Wehling-Henricks M, et al. Among authors: welc ss. Hum Mol Genet. 2018 Jan 1;27(1):14-29. doi: 10.1093/hmg/ddx380. Hum Mol Genet. 2018. PMID: 29040534 Free PMC article.

4

Aging of the immune system causes reductions in muscle stem cell populations, promotes their shift to a fibrogenic phenotype, and modulates sarcopenia.

Wang Y, Wehling-Henricks M, Welc SS, Fisher AL, Zuo Q, Tidball JG. Wang Y, et al. Among authors: welc ss. FASEB J. 2019 Jan;33(1):1415-1427. doi: 10.1096/fj.201800973R. Epub 2018 Aug 21. FASEB J. 2019. PMID: 30130434 Free PMC article.

5

Immunobiology of Inherited Muscular Dystrophies.

Tidball JG, Welc SS, Wehling-Henricks M. Tidball JG, et al. Among authors: welc ss. Compr Physiol. 2018 Sep 14;8(4):1313-1356. doi: 10.1002/cphy.c170052. Compr Physiol. 2018. PMID: 30215857 Free PMC article. Review.

6

Myeloid cell-derived tumor necrosis factor-alpha promotes sarcopenia and regulates muscle cell fusion with aging muscle fibers.

Wang Y, Welc SS, Wehling-Henricks M, Tidball JG. Wang Y, et al. Among authors: welc ss. Aging Cell. 2018 Dec;17(6):e12828. doi: 10.1111/acel.12828. Epub 2018 Sep 6. Aging Cell. 2018. PMID: 30256507 Free PMC article.

7

Aging of the immune system and impaired muscle regeneration: A failure of immunomodulation of adult myogenesis.

Tidball JG, Flores I, Welc SS, Wehling-Henricks M, Ochi E. Tidball JG, et al. Among authors: welc ss. Exp Gerontol. 2021 Mar;145:111200. doi: 10.1016/j.exger.2020.111200. Epub 2020 Dec 24. Exp Gerontol. 2021. PMID: 33359378 Free PMC article. Review.

8

Myeloid cell-mediated targeting of LIF to dystrophic muscle causes transient increases in muscle fiber lesions by disrupting the recruitment and dispersion of macrophages in muscle.

Flores I, Welc SS, Wehling-Henricks M, Tidball JG. Flores I, et al. Among authors: welc ss. Hum Mol Genet. 2021 Dec 27;31(2):189-206. doi: 10.1093/hmg/ddab230. Hum Mol Genet. 2021. PMID: 34392367 Free PMC article.

9

Macrophage-Derived IGF-1 Is a Potent Coordinator of Myogenesis and Inflammation in Regenerating Muscle.

Tidball JG, Welc SS. Tidball JG, et al. Among authors: welc ss. Mol Ther. 2015 Jul;23(7):1134-1135. doi: 10.1038/mt.2015.97. Mol Ther. 2015. PMID: 26122828 Free PMC article. No abstract available.

10

Myeloid cells are capable of synthesizing aldosterone to exacerbate damage in muscular dystrophy.

Chadwick JA, Swager SA, Lowe J, Welc SS, Tidball JG, Gomez-Sanchez CE, Gomez-Sanchez EP, Rafael-Fortney JA. Chadwick JA, et al. Among authors: welc ss. Hum Mol Genet. 2016 Dec 1;25(23):5167-5177. doi: 10.1093/hmg/ddw331. Hum Mol Genet. 2016. PMID: 27798095 Free PMC article.

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