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251 results

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Genetic variation in GNB5 causes bradycardia by augmenting the cholinergic response via increased acetylcholine-activated potassium current (IK,ACh).
Veerman CC, Mengarelli I, Koopman CD, Wilders R, van Amersfoorth SC, Bakker D, Wolswinkel R, Hababa M, de Boer TP, Guan K, Milnes J, Lodder EM, Bakkers J, Verkerk AO, Bezzina CR. Veerman CC, et al. Among authors: bezzina cr. Dis Model Mech. 2019 Jul 9;12(7):dmm037994. doi: 10.1242/dmm.037994. Dis Model Mech. 2019. PMID: 31208990 Free PMC article.
Genetic control of sodium channel function.
Tan HL, Bezzina CR, Smits JP, Verkerk AO, Wilde AA. Tan HL, et al. Among authors: bezzina cr. Cardiovasc Res. 2003 Mar 15;57(4):961-73. doi: 10.1016/s0008-6363(02)00714-9. Cardiovasc Res. 2003. PMID: 12650874 Review.
A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization.
Bezzina CR, Verkerk AO, Busjahn A, Jeron A, Erdmann J, Koopmann TT, Bhuiyan ZA, Wilders R, Mannens MM, Tan HL, Luft FC, Schunkert H, Wilde AA. Bezzina CR, et al. Cardiovasc Res. 2003 Jul 1;59(1):27-36. doi: 10.1016/s0008-6363(03)00342-0. Cardiovasc Res. 2003. PMID: 12829173
Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: a combined electrophysiological, genetic, histopathologic, and computational study.
Coronel R, Casini S, Koopmann TT, Wilms-Schopman FJ, Verkerk AO, de Groot JR, Bhuiyan Z, Bezzina CR, Veldkamp MW, Linnenbank AC, van der Wal AC, Tan HL, Brugada P, Wilde AA, de Bakker JM. Coronel R, et al. Among authors: bezzina cr. Circulation. 2005 Nov 1;112(18):2769-77. doi: 10.1161/CIRCULATIONAHA.105.532614. Circulation. 2005. PMID: 16267250
Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD.
Remme CA, Verkerk AO, Nuyens D, van Ginneken AC, van Brunschot S, Belterman CN, Wilders R, van Roon MA, Tan HL, Wilde AA, Carmeliet P, de Bakker JM, Veldkamp MW, Bezzina CR. Remme CA, et al. Among authors: bezzina cr. Circulation. 2006 Dec 12;114(24):2584-94. doi: 10.1161/CIRCULATIONAHA.106.653949. Epub 2006 Dec 4. Circulation. 2006. PMID: 17145985
The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium.
Remme CA, Verkerk AO, Hoogaars WM, Aanhaanen WT, Scicluna BP, Annink C, van den Hoff MJ, Wilde AA, van Veen TA, Veldkamp MW, de Bakker JM, Christoffels VM, Bezzina CR. Remme CA, et al. Among authors: bezzina cr. Basic Res Cardiol. 2009 Sep;104(5):511-22. doi: 10.1007/s00395-009-0012-8. Epub 2009 Mar 3. Basic Res Cardiol. 2009. PMID: 19255801 Free PMC article.
251 results