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Inhibition of pro-inflammatory cytokine production by the dual p38/JNK2 inhibitor BIRB796 correlates with the inhibition of p38 signaling.
Gruenbaum LM, Schwartz R, Woska JR Jr, DeLeon RP, Peet GW, Warren TC, Capolino A, Mara L, Morelock MM, Shrutkowski A, Jones JW, Pargellis CA. Gruenbaum LM, et al. Among authors: deleon rp. Biochem Pharmacol. 2009 Feb 1;77(3):422-32. doi: 10.1016/j.bcp.2008.10.032. Epub 2008 Nov 5. Biochem Pharmacol. 2009. PMID: 19027720
Identification of dissociated non-steroidal glucocorticoid receptor agonists.
Kuzmich D, Kirrane T, Proudfoot J, Bekkali Y, Zindell R, Beck L, Nelson R, Shih CK, Kukulka AJ, Paw Z, Reilly P, Deleon R, Cardozo M, Nabozny G, Thomson D. Kuzmich D, et al. Among authors: deleon r. Bioorg Med Chem Lett. 2007 Sep 15;17(18):5025-31. doi: 10.1016/j.bmcl.2007.07.031. Epub 2007 Jul 25. Bioorg Med Chem Lett. 2007. PMID: 17692519
Pyrazinoindolone inhibitors of MAPKAP-K2.
Goldberg DR, Choi Y, Cogan D, Corson M, DeLeon R, Gao A, Gruenbaum L, Hao MH, Joseph D, Kashem MA, Miller C, Moss N, Netherton MR, Pargellis CP, Pelletier J, Sellati R, Skow D, Torcellini C, Tseng YC, Wang J, Wasti R, Werneburg B, Wu JP, Xiong Z. Goldberg DR, et al. Among authors: deleon r. Bioorg Med Chem Lett. 2008 Feb 1;18(3):938-41. doi: 10.1016/j.bmcl.2007.12.037. Epub 2007 Dec 23. Bioorg Med Chem Lett. 2008. PMID: 18221871
51 results