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Dihomo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis.
Gallagher H, Williams JO, Ferekidis N, Ismail A, Chan YH, Michael DR, Guschina IA, Tyrrell VJ, O'Donnell VB, Harwood JL, Khozin-Goldberg I, Boussiba S, Ramji DP. Gallagher H, et al. Among authors: michael dr. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2538-2550. doi: 10.1016/j.bbadis.2019.06.011. Epub 2019 Jun 13. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 31202985 Free PMC article.
Sp1 and Sp3 mediate constitutive transcription of the human hyaluronan synthase 2 gene.
Monslow J, Williams JD, Fraser DJ, Michael DR, Foka P, Kift-Morgan AP, Luo DD, Fielding CA, Craig KJ, Topley N, Jones SA, Ramji DP, Bowen T. Monslow J, et al. Among authors: michael dr. J Biol Chem. 2006 Jun 30;281(26):18043-50. doi: 10.1074/jbc.M510467200. Epub 2006 Apr 7. J Biol Chem. 2006. PMID: 16603733 Free article.
IL-33 reduces macrophage foam cell formation.
McLaren JE, Michael DR, Salter RC, Ashlin TG, Calder CJ, Miller AM, Liew FY, Ramji DP. McLaren JE, et al. Among authors: michael dr. J Immunol. 2010 Jul 15;185(2):1222-9. doi: 10.4049/jimmunol.1000520. Epub 2010 Jun 11. J Immunol. 2010. PMID: 20543107
The expression of a disintegrin and metalloproteinase with thrombospondin motifs 4 in human macrophages is inhibited by the anti-atherogenic cytokine transforming growth factor-β and requires Smads, p38 mitogen-activated protein kinase and c-Jun.
Salter RC, Arnaoutakis K, Michael DR, Singh NN, Ashlin TG, Buckley ML, Kwan AP, Ramji DP. Salter RC, et al. Among authors: michael dr. Int J Biochem Cell Biol. 2011 May;43(5):805-11. doi: 10.1016/j.biocel.2011.02.005. Epub 2011 Feb 18. Int J Biochem Cell Biol. 2011. PMID: 21334453 Free PMC article.
Liver X receptors, atherosclerosis and inflammation.
Michael DR, Ashlin TG, Buckley ML, Ramji DP. Michael DR, et al. Curr Atheroscler Rep. 2012 Jun;14(3):284-93. doi: 10.1007/s11883-012-0239-y. Curr Atheroscler Rep. 2012. PMID: 22419222 Review.
48 results