Pan CQ - Search Results

1

Engineering an anti-CD52 antibody for enhanced deamidation stability.

Qiu H, Wei R, Jaworski J, Boudanova E, Hughes H, VanPatten S, Lund A, Day J, Zhou Y, McSherry T, Pan CQ, Sendak R. Qiu H, et al. Among authors: pan cq. MAbs. 2019 Oct;11(7):1266-1275. doi: 10.1080/19420862.2019.1631117. Epub 2019 Jul 18. MAbs. 2019. PMID: 31199181 Free PMC article.

2

Engineered Fc-glycosylation switch to eliminate antibody effector function.

Zhou Q, Jaworski J, Zhou Y, Valente D, Cotton J, Honey D, Boudanova E, Beninga J, Rao E, Wei R, Mauriac C, Pan C, Park A, Qiu H. Zhou Q, et al. MAbs. 2020 Jan-Dec;12(1):1814583. doi: 10.1080/19420862.2020.1814583. MAbs. 2020. PMID: 32892677 Free PMC article.

3

Impact of cysteine variants on the structure, activity, and stability of recombinant human α-galactosidase A.

Qiu H, Honey DM, Kingsbury JS, Park A, Boudanova E, Wei RR, Pan CQ, Edmunds T. Qiu H, et al. Among authors: pan cq. Protein Sci. 2015 Sep;24(9):1401-11. doi: 10.1002/pro.2719. Epub 2015 Jul 14. Protein Sci. 2015. PMID: 26044846 Free PMC article.

4

X-ray and biochemical analysis of N370S mutant human acid β-glucosidase.

Wei RR, Hughes H, Boucher S, Bird JJ, Guziewicz N, Van Patten SM, Qiu H, Pan CQ, Edmunds T. Wei RR, et al. Among authors: pan cq. J Biol Chem. 2011 Jan 7;286(1):299-308. doi: 10.1074/jbc.M110.150433. Epub 2010 Oct 27. J Biol Chem. 2011. PMID: 20980263 Free PMC article.

5

High-affinity VEGF antagonists by oligomerization of a minimal sequence VEGF-binding domain.

Stefano JE, Bird J, Kyazike J, Cheng AW, Boudanova E, Dwyer M, Hou L, Qiu H, Matthews G, O'Callaghan M, Pan CQ. Stefano JE, et al. Among authors: pan cq. Bioconjug Chem. 2012 Dec 19;23(12):2354-64. doi: 10.1021/bc300301m. Epub 2012 Dec 10. Bioconjug Chem. 2012. PMID: 23176598

6

Structures of a pan-specific antagonist antibody complexed to different isoforms of TGFβ reveal structural plasticity of antibody-antigen interactions.

Moulin A, Mathieu M, Lawrence C, Bigelow R, Levine M, Hamel C, Marquette JP, Le Parc J, Loux C, Ferrari P, Capdevila C, Dumas J, Dumas B, Rak A, Bird J, Qiu H, Pan CQ, Edmunds T, Wei RR. Moulin A, et al. Among authors: pan cq. Protein Sci. 2014 Dec;23(12):1698-707. doi: 10.1002/pro.2548. Epub 2014 Sep 26. Protein Sci. 2014. PMID: 25209176 Free PMC article.

7

Site-specific PEGylation of human thyroid stimulating hormone to prolong duration of action.

Qiu H, Boudanova E, Park A, Bird JJ, Honey DM, Zarazinski C, Greene B, Kingsbury JS, Boucher S, Pollock J, McPherson JM, Pan CQ. Qiu H, et al. Among authors: pan cq. Bioconjug Chem. 2013 Mar 20;24(3):408-18. doi: 10.1021/bc300519h. Epub 2013 Feb 11. Bioconjug Chem. 2013. PMID: 23350694

8

Strategies for Neoglycan conjugation to human acid α-glucosidase.

Zhou Q, Stefano JE, Harrahy J, Finn P, Avila L, Kyazike J, Wei R, Van Patten SM, Gotschall R, Zheng X, Zhu Y, Edmunds T, Pan CQ. Zhou Q, et al. Among authors: pan cq. Bioconjug Chem. 2011 Apr 20;22(4):741-51. doi: 10.1021/bc1005416. Epub 2011 Mar 18. Bioconjug Chem. 2011. PMID: 21417264

9

Development of a simple and rapid method for producing non-fucosylated oligomannose containing antibodies with increased effector function.

Zhou Q, Shankara S, Roy A, Qiu H, Estes S, McVie-Wylie A, Culm-Merdek K, Park A, Pan C, Edmunds T. Zhou Q, et al. Biotechnol Bioeng. 2008 Feb 15;99(3):652-65. doi: 10.1002/bit.21598. Biotechnol Bioeng. 2008. PMID: 17680659

10

Carbohydrate-mediated polyethylene glycol conjugation of TSH improves its pharmacological properties.

Park A, Honey DM, Hou L, Bird JJ, Zarazinski C, Searles M, Braithwaite C, Kingsbury JS, Kyazike J, Culm-Merdek K, Greene B, Stefano JE, Qiu H, McPherson JM, Pan CQ. Park A, et al. Among authors: pan cq. Endocrinology. 2013 Mar;154(3):1373-83. doi: 10.1210/en.2012-2010. Epub 2013 Feb 6. Endocrinology. 2013. PMID: 23389953

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