He J - Search Results

1

Anti-Tumor Study of H6, a 4-Substituted Coumarins Derivative, Loaded Biodegradable Self-Assembly Nano-Micelles In Vitro and In Vivo.

Zhu Z, Su Z, Yang J, Liu H, Tang M, Hu Q, Bai P, Wen J, He J, Niu T, Chen L. Zhu Z, et al. Among authors: he j. J Biomed Nanotechnol. 2019 Jul 1;15(7):1515-1531. doi: 10.1166/jbn.2019.2797. J Biomed Nanotechnol. 2019. PMID: 31196355

2

Therapeutic efficacy of an injectable formulation of purinostat mesylate in SU-DHL-6 tumour model.

Zhu Z, Wen J, Xu Y, Pei H, Li D, Tang M, Bai P, He J, Yang Z, Chen L. Zhu Z, et al. Among authors: he j. Ann Med. 2022 Dec;54(1):743-753. doi: 10.1080/07853890.2022.2045347. Ann Med. 2022. PMID: 35243950 Free PMC article.

3

Identification of Pyrrolo[2,3- d]pyrimidine-Based Derivatives as Potent and Orally Effective Fms-like Tyrosine Receptor Kinase 3 (FLT3) Inhibitors for Treating Acute Myelogenous Leukemia.

Yuan X, Chen Y, Zhang W, He J, Lei L, Tang M, Liu J, Li M, Dou C, Yang T, Yang L, Yang S, Wei Y, Peng A, Niu T, Xiang M, Ye H, Chen L. Yuan X, et al. Among authors: he j. J Med Chem. 2019 Apr 25;62(8):4158-4173. doi: 10.1021/acs.jmedchem.9b00223. Epub 2019 Apr 15. J Med Chem. 2019. PMID: 30939008

4

Discovery of Potent and Orally Effective Dual Janus Kinase 2/FLT3 Inhibitors for the Treatment of Acute Myelogenous Leukemia and Myeloproliferative Neoplasms.

Yang T, Hu M, Qi W, Yang Z, Tang M, He J, Chen Y, Bai P, Yuan X, Zhang C, Liu K, Lu Y, Xiang M, Chen L. Yang T, et al. Among authors: he j. J Med Chem. 2019 Nov 27;62(22):10305-10320. doi: 10.1021/acs.jmedchem.9b01348. Epub 2019 Nov 8. J Med Chem. 2019. PMID: 31670517

5

Discovery of Novel Dual Histone Deacetylase and Mammalian Target of Rapamycin Target Inhibitors as a Promising Strategy for Cancer Therapy.

Chen Y, Yuan X, Zhang W, Tang M, Zheng L, Wang F, Yan W, Yang S, Wei Y, He J, Chen L. Chen Y, et al. Among authors: he j. J Med Chem. 2019 Feb 14;62(3):1577-1592. doi: 10.1021/acs.jmedchem.8b01825. Epub 2019 Jan 24. J Med Chem. 2019. PMID: 30629434

6

Design, synthesis and evaluation of novel 7H-pyrrolo[2,3-d]pyrimidin-4-amine derivatives as potent, selective and reversible Bruton's tyrosine kinase (BTK) inhibitors for the treatment of rheumatoid arthritis.

Zhang C, Pei H, He J, Zhu J, Li W, Niu T, Xiang M, Chen L. Zhang C, et al. Among authors: he j. Eur J Med Chem. 2019 May 1;169:121-143. doi: 10.1016/j.ejmech.2019.02.077. Epub 2019 Mar 6. Eur J Med Chem. 2019. PMID: 30875504

7

Correction to "Discovery of Potent and Orally Effective Dual Janus Kinase 2/FLT3 Inhibitors for the Treatment of Acute Myelogenous Leukemia and Myeloproliferative Neoplasms".

Yang T, Hu M, Qi W, Yang Z, Tang M, He J, Chen Y, Bai P, Yuan X, Zhang C, Liu K, Lu Y, Xiang M, Chen L. Yang T, et al. Among authors: he j. J Med Chem. 2020 Feb 13;63(3):1441-1442. doi: 10.1021/acs.jmedchem.0c00025. Epub 2020 Jan 27. J Med Chem. 2020. PMID: 31985218 No abstract available.

8

N-(Pyrimidin-2-yl)-1,2,3,4-tetrahydroisoquinolin-6-amine Derivatives as Selective Janus Kinase 2 Inhibitors for the Treatment of Myeloproliferative Neoplasms.

Yang T, Hu M, Chen Y, Xiang M, Tang M, Qi W, Shi M, He J, Yuan X, Zhang C, Liu K, Li J, Yang Z, Chen L. Yang T, et al. Among authors: he j. J Med Chem. 2020 Dec 10;63(23):14921-14936. doi: 10.1021/acs.jmedchem.0c01488. Epub 2020 Nov 30. J Med Chem. 2020. PMID: 33256400

9

Correction to "N-(Pyrimidin-2-yl)-1,2,3,4-tetrahydroisoquinolin-6-amine Derivatives as Selective Janus Kinase 2 Inhibitors for the Treatment of Myeloproliferative Neoplasms".

Yang T, Hu M, Chen Y, Xiang M, Tang M, Qi W, Shi M, He J, Yuan X, Zhang C, Liu K, Li J, Yang Z, Chen L. Yang T, et al. Among authors: he j. J Med Chem. 2021 Feb 25;64(4):2310. doi: 10.1021/acs.jmedchem.1c00198. Epub 2021 Feb 16. J Med Chem. 2021. PMID: 33591746 No abstract available.

10

Emerging targets and potential therapeutic agents in non-alcoholic fatty liver disease treatment.

Yang Y, Zhao Y, Li W, Wu Y, Wang X, Wang Y, Liu T, Ye T, Xie Y, Cheng Z, He J, Bai P, Zhang Y, Ouyang L. Yang Y, et al. Among authors: he j. Eur J Med Chem. 2020 Jul 1;197:112311. doi: 10.1016/j.ejmech.2020.112311. Epub 2020 Apr 18. Eur J Med Chem. 2020. PMID: 32339855 Review.

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