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Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation.
Da Costa EM, Armaos G, McInnes G, Beaudry A, Moquin-Beaudry G, Bertrand-Lehouillier V, Caron M, Richer C, St-Onge P, Johnson JR, Krogan N, Sai Y, Downey M, Rafei M, Boileau M, Eppert K, Flores-Díaz E, Haman A, Hoang T, Sinnett D, Beauséjour C, McGraw S, Raynal NJ. Da Costa EM, et al. Among authors: mcinnes g. J Exp Clin Cancer Res. 2019 Jun 13;38(1):251. doi: 10.1186/s13046-019-1242-8. J Exp Clin Cancer Res. 2019. PMID: 31196146 Free PMC article.
DNA Methylation-Targeted Drugs.
Da Costa EM, McInnes G, Beaudry A, Raynal NJ. Da Costa EM, et al. Among authors: mcinnes g. Cancer J. 2017 Sep/Oct;23(5):270-276. doi: 10.1097/PPO.0000000000000278. Cancer J. 2017. PMID: 28926427 Review.
Apolipoprotein C3 induces inflammasome activation only in its delipidated form.
Hsu CC, Shao B, Kanter JE, He Y, Vaisar T, Witztum JL, Snell-Bergeon J, McInnes G, Bruse S, Gottesman O, Mullick AE, Bornfeldt KE. Hsu CC, et al. Among authors: mcinnes g. Nat Immunol. 2023 Mar;24(3):408-411. doi: 10.1038/s41590-023-01423-2. Epub 2023 Feb 13. Nat Immunol. 2023. PMID: 36781985 Free PMC article.
Functional genomics of OCTN2 variants informs protein-specific variant effect predictor for Carnitine Transporter Deficiency.
Koleske ML, McInnes G, Brown JEH, Thomas N, Hutchinson K, Chin MY, Koehl A, Arkin MR, Schlessinger A, Gallagher RC, Song YS, Altman RB, Giacomini KM. Koleske ML, et al. Among authors: mcinnes g. Proc Natl Acad Sci U S A. 2022 Nov 16;119(46):e2210247119. doi: 10.1073/pnas.2210247119. Epub 2022 Nov 7. Proc Natl Acad Sci U S A. 2022. PMID: 36343260 Free PMC article.
Genetic Variation among Pharmacogenes in the Sardinian Population.
Idda ML, Zoledziewska M, Urru SAM, McInnes G, Bilotta A, Nuvoli V, Lodde V, Orrù S, Schlessinger D, Cucca F, Floris M. Idda ML, et al. Among authors: mcinnes g. Int J Mol Sci. 2022 Sep 2;23(17):10058. doi: 10.3390/ijms231710058. Int J Mol Sci. 2022. PMID: 36077453 Free PMC article.
Genomewide Association Studies in Pharmacogenomics.
McInnes G, Yee SW, Pershad Y, Altman RB. McInnes G, et al. Clin Pharmacol Ther. 2021 Sep;110(3):637-648. doi: 10.1002/cpt.2349. Epub 2021 Jul 18. Clin Pharmacol Ther. 2021. PMID: 34185318 Free PMC article. Review.
270 results