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Evaluating the effects of fluorine on biological properties and metabolic stability of some antitubulin 3-substituted 7-phenyl-pyrroloquinolinones.
Bortolozzi R, Carta D, Prà MD, Antoniazzi G, Mattiuzzo E, Sturlese M, Di Paolo V, Calderan L, Moro S, Hamel E, Quintieri L, Ronca R, Viola G, Ferlin MG. Bortolozzi R, et al. Among authors: quintieri l. Eur J Med Chem. 2019 Sep 15;178:297-314. doi: 10.1016/j.ejmech.2019.05.092. Epub 2019 Jun 3. Eur J Med Chem. 2019. PMID: 31195171
A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts.
De Luca A, Rotili D, Carpanese D, Lenoci A, Calderan L, Scimeca M, Mai A, Bonanno E, Rosato A, Geroni C, Quintieri L, Caccuri AM. De Luca A, et al. Among authors: quintieri l. Oncotarget. 2015 Feb 28;6(6):4126-43. doi: 10.18632/oncotarget.2798. Oncotarget. 2015. PMID: 25595904 Free PMC article.
Thiol-Activated Anticancer Agents: The State of the Art.
Dalzoppo D, Di Paolo V, Calderan L, Pasut G, Rosato A, Caccuri AM, Quintieri L. Dalzoppo D, et al. Among authors: quintieri l. Anticancer Agents Med Chem. 2017;17(1):4-20. Anticancer Agents Med Chem. 2017. PMID: 27539318 Review.
Synthesis, structure-activity relationships and biological evaluation of 7-phenyl-pyrroloquinolinone 3-amide derivatives as potent antimitotic agents.
Carta D, Bortolozzi R, Sturlese M, Salmaso V, Hamel E, Basso G, Calderan L, Quintieri L, Moro S, Viola G, Ferlin MG. Carta D, et al. Among authors: quintieri l. Eur J Med Chem. 2017 Feb 15;127:643-660. doi: 10.1016/j.ejmech.2016.10.026. Epub 2016 Oct 21. Eur J Med Chem. 2017. PMID: 27823884 Free PMC article.
LKB1 loss is associated with glutathione deficiency under oxidative stress and sensitivity of cancer cells to cytotoxic drugs and γ-irradiation.
Zulato E, Ciccarese F, Agnusdei V, Pinazza M, Nardo G, Iorio E, Curtarello M, Silic-Benussi M, Rossi E, Venturoli C, Panieri E, Santoro MM, Di Paolo V, Quintieri L, Ciminale V, Indraccolo S. Zulato E, et al. Among authors: quintieri l. Biochem Pharmacol. 2018 Oct;156:479-490. doi: 10.1016/j.bcp.2018.09.019. Epub 2018 Sep 15. Biochem Pharmacol. 2018. PMID: 30222967
Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis.
Di Paolo V, Fulci C, Rotili D, Sciarretta F, Lucidi A, Morozzo Della Rocca B, De Luca A, Rosato A, Quintieri L, Caccuri AM. Di Paolo V, et al. Among authors: quintieri l. J Enzyme Inhib Med Chem. 2019 Dec;34(1):1131-1139. doi: 10.1080/14756366.2019.1617287. J Enzyme Inhib Med Chem. 2019. PMID: 31169043 Free PMC article.
94 results