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Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II).
D'Alessandro S, Alfano G, Di Cerbo L, Brogi S, Chemi G, Relitti N, Brindisi M, Lamponi S, Novellino E, Campiani G, Gemma S, Basilico N, Taramelli D, Baratto MC, Pogni R, Butini S. D'Alessandro S, et al. Among authors: relitti n. Bioorg Chem. 2019 Aug;89:103020. doi: 10.1016/j.bioorg.2019.103020. Epub 2019 May 31. Bioorg Chem. 2019. PMID: 31185392
Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors.
Campiani G, Cavella C, Osko JD, Brindisi M, Relitti N, Brogi S, Saraswati AP, Federico S, Chemi G, Maramai S, Carullo G, Jaeger B, Carleo A, Benedetti R, Sarno F, Lamponi S, Rottoli P, Bargagli E, Bertucci C, Tedesco D, Herp D, Senger J, Ruberti G, Saccoccia F, Saponara S, Gorelli B, Valoti M, Kennedy B, Sundaramurthi H, Butini S, Jung M, Roach KM, Altucci L, Bradding P, Christianson DW, Gemma S, Prasse A. Campiani G, et al. Among authors: relitti n. J Med Chem. 2021 Jul 22;64(14):9960-9988. doi: 10.1021/acs.jmedchem.1c00184. Epub 2021 Jul 12. J Med Chem. 2021. PMID: 34251197 Free PMC article.
Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation.
Relitti N, Saraswati AP, Chemi G, Brindisi M, Brogi S, Herp D, Schmidtkunz K, Saccoccia F, Ruberti G, Ulivieri C, Vanni F, Sarno F, Altucci L, Lamponi S, Jung M, Gemma S, Butini S, Campiani G. Relitti N, et al. Eur J Med Chem. 2021 Feb 15;212:112998. doi: 10.1016/j.ejmech.2020.112998. Epub 2020 Nov 7. Eur J Med Chem. 2021. PMID: 33199154
Synthesis and biological evaluation of benzhydryl-based antiplasmodial agents possessing Plasmodium falciparum chloroquine resistance transporter (PfCRT) inhibitory activity.
Relitti N, Federico S, Pozzetti L, Butini S, Lamponi S, Taramelli D, D'Alessandro S, Martin RE, Shafik SH, Summers RL, Babij SK, Habluetzel A, Tapanelli S, Caldelari R, Gemma S, Campiani G. Relitti N, et al. Eur J Med Chem. 2021 Apr 5;215:113227. doi: 10.1016/j.ejmech.2021.113227. Epub 2021 Feb 6. Eur J Med Chem. 2021. PMID: 33601312
Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems.
Grillo A, Chemi G, Brogi S, Brindisi M, Relitti N, Fezza F, Fazio D, Castelletti L, Perdona E, Wong A, Lamponi S, Pecorelli A, Benedusi M, Fantacci M, Valoti M, Valacchi G, Micheli F, Novellino E, Campiani G, Butini S, Maccarrone M, Gemma S. Grillo A, et al. Among authors: relitti n. Eur J Med Chem. 2019 Dec 1;183:111674. doi: 10.1016/j.ejmech.2019.111674. Epub 2019 Sep 4. Eur J Med Chem. 2019. PMID: 31518969
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