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220 results

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Page 1
Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II).
D'Alessandro S, Alfano G, Di Cerbo L, Brogi S, Chemi G, Relitti N, Brindisi M, Lamponi S, Novellino E, Campiani G, Gemma S, Basilico N, Taramelli D, Baratto MC, Pogni R, Butini S. D'Alessandro S, et al. Among authors: alfano g. Bioorg Chem. 2019 Aug;89:103020. doi: 10.1016/j.bioorg.2019.103020. Epub 2019 May 31. Bioorg Chem. 2019. PMID: 31185392
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues.
Vallone A, D'Alessandro S, Brogi S, Brindisi M, Chemi G, Alfano G, Lamponi S, Lee SG, Jez JM, Koolen KJM, Dechering KJ, Saponara S, Fusi F, Gorelli B, Taramelli D, Parapini S, Caldelari R, Campiani G, Gemma S, Butini S. Vallone A, et al. Among authors: alfano g. Eur J Med Chem. 2018 Apr 25;150:698-718. doi: 10.1016/j.ejmech.2018.03.024. Epub 2018 Mar 10. Eur J Med Chem. 2018. PMID: 29571157 Free PMC article.
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents.
Brindisi M, Ulivieri C, Alfano G, Gemma S, de Asís Balaguer F, Khan T, Grillo A, Chemi G, Menchon G, Prota AE, Olieric N, Lucena-Agell D, Barasoain I, Diaz JF, Nebbioso A, Conte M, Lopresti L, Magnano S, Amet R, Kinsella P, Zisterer DM, Ibrahim O, O'Sullivan J, Morbidelli L, Spaccapelo R, Baldari C, Butini S, Novellino E, Campiani G, Altucci L, Steinmetz MO, Brogi S. Brindisi M, et al. Among authors: alfano g. Eur J Med Chem. 2019 Jan 15;162:290-320. doi: 10.1016/j.ejmech.2018.11.004. Epub 2018 Nov 3. Eur J Med Chem. 2019. PMID: 30448418
First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents.
Brogi S, Ramunno A, Savi L, Chemi G, Alfano G, Pecorelli A, Pambianchi E, Galatello P, Compagnoni G, Focher F, Biamonti G, Valacchi G, Butini S, Gemma S, Campiani G, Brindisi M. Brogi S, et al. Among authors: alfano g. Eur J Med Chem. 2017 Sep 29;138:438-457. doi: 10.1016/j.ejmech.2017.06.017. Epub 2017 Jun 9. Eur J Med Chem. 2017. PMID: 28689095
Site-directed Mutagenesis of Key Residues Unveiled a Novel Allosteric Site on Human Adenosine Kinase for Pyrrolobenzoxa(thia)zepinone Non-Nucleoside Inhibitors.
Savi L, Brindisi M, Alfano G, Butini S, La Pietra V, Novellino E, Marinelli L, Lossani A, Focher F, Cavella C, Campiani G, Gemma S. Savi L, et al. Among authors: alfano g. Chem Biol Drug Des. 2016 Jan;87(1):112-20. doi: 10.1111/cbdd.12630. Epub 2015 Sep 18. Chem Biol Drug Des. 2016. PMID: 26242695
Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans.
Vicencio JM, Evans R, Green R, An Z, Deng J, Treacy C, Mustapha R, Monypenny J, Costoya C, Lawler K, Ng K, De-Souza K, Coban O, Gomez V, Clancy J, Chen SH, Chalk A, Wong F, Gordon P, Savage C, Gomes C, Pan T, Alfano G, Dolcetti L, Chan JNE, Flores-Borja F, Barber PR, Weitsman G, Sosnowska D, Capone E, Iacobelli S, Hochhauser D, Hartley JA, Parsons M, Arnold JN, Ameer-Beg S, Quezada SA, Yarden Y, Sala G, Ng T. Vicencio JM, et al. Among authors: alfano g. Cell Death Dis. 2022 Mar 28;13(3):274. doi: 10.1038/s41419-022-04701-3. Cell Death Dis. 2022. PMID: 35347108 Free PMC article.
Screening for nasal carriage of Staphylococcus (S.) aureus reduces the risk of S. aureus peritonitis in patients on peritoneal dialysis (PD).
Alfano G, Pittiglio M, Ferri C, Romaniello R, Oliviero G, Cancelli Y, Melara L, Tonelli L, Montani M, Raimondo D, Morisi N, Ligabue G, Giovanella S, Fontana F, Magistroni R, Donati G. Alfano G, et al. Int Urol Nephrol. 2024 Dec 30. doi: 10.1007/s11255-024-04309-w. Online ahead of print. Int Urol Nephrol. 2024. PMID: 39738858
Improving the sustainability and quality of kidney health care through life cycle assessments, quality improvement, education and technical innovations: the KitNewCare approach.
Duane B, Steinbach I, Stancliffe R, Barna S, Cameron D, de Barbieri I, Noruisiene E, Mortimer F, Gerritsen K, Vanholder R, Donati G, Alfano G, Malyszko J, Ligabue G, Johnston B, Wratten ML, Caiazzo M, Schmid E, Ortiz A. Duane B, et al. Among authors: alfano g. J Nephrol. 2024 Nov 8. doi: 10.1007/s40620-024-02114-3. Online ahead of print. J Nephrol. 2024. PMID: 39511063
220 results