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Page 1
Biological activity and stability analyses of knipholone anthrone, a phenyl anthraquinone derivative isolated from Kniphofia foliosa Hochst.
Feilcke R, Arnouk G, Raphane B, Richard K, Tietjen I, Andrae-Marobela K, Erdmann F, Schipper S, Becker K, Arnold N, Frolov A, Reiling N, Imming P, Fobofou SAT. Feilcke R, et al. Among authors: tietjen i. J Pharm Biomed Anal. 2019 Sep 10;174:277-285. doi: 10.1016/j.jpba.2019.05.065. Epub 2019 May 31. J Pharm Biomed Anal. 2019. PMID: 31185339
Thorectidiol A Isolated from the Marine Sponge Dactylospongia elegans Disrupts Interactions of the SARS-CoV-2 Spike Receptor Binding Domain with the Host ACE2 Receptor.
Williams DE, Cassel J, Zhu JL, Yang JX, de Voogd NJ, Matainaho T, Salvino JM, Wang YA, Montaner LJ, Tietjen I, Andersen RJ. Williams DE, et al. Among authors: tietjen i. J Nat Prod. 2023 Mar 24;86(3):582-588. doi: 10.1021/acs.jnatprod.2c01030. Epub 2023 Jan 19. J Nat Prod. 2023. PMID: 36657039 Free PMC article.
Croton megalobotrys Müll Arg. and Vitex doniana (Sweet): Traditional medicinal plants in a three-step treatment regimen that inhibit in vitro replication of HIV-1.
Tietjen I, Gatonye T, Ngwenya BN, Namushe A, Simonambanga S, Muzila M, Mwimanzi P, Xiao J, Fedida D, Brumme ZL, Brockman MA, Andrae-Marobela K. Tietjen I, et al. J Ethnopharmacol. 2016 Sep 15;191:331-340. doi: 10.1016/j.jep.2016.06.040. Epub 2016 Jun 24. J Ethnopharmacol. 2016. PMID: 27350006
The Croton megalobotrys Müll Arg. traditional medicine in HIV/AIDS management: Documentation of patient use, in vitro activation of latent HIV-1 provirus, and isolation of active phorbol esters.
Tietjen I, Ngwenya BN, Fotso G, Williams DE, Simonambango S, Ngadjui BT, Andersen RJ, Brockman MA, Brumme ZL, Andrae-Marobela K. Tietjen I, et al. J Ethnopharmacol. 2018 Jan 30;211:267-277. doi: 10.1016/j.jep.2017.09.038. Epub 2017 Sep 29. J Ethnopharmacol. 2018. PMID: 28970153
The African natural product knipholone anthrone and its analogue anthralin (dithranol) enhance HIV-1 latency reversal.
Richard K, Schonhofer C, Giron LB, Rivera-Ortiz J, Read S, Kannan T, Kinloch NN, Shahid A, Feilcke R, Wappler S, Imming P, Harris M, Brumme ZL, Brockman MA, Mounzer K, Kossenkov AV, Abdel-Mohsen M, Andrae-Marobela K, Montaner LJ, Tietjen I. Richard K, et al. Among authors: tietjen i. J Biol Chem. 2020 Oct 9;295(41):14084-14099. doi: 10.1074/jbc.RA120.013031. Epub 2020 Aug 11. J Biol Chem. 2020. PMID: 32788215 Free PMC article.
Flavonoid-based inhibition of cyclin-dependent kinase 9 without concomitant inhibition of histone deacetylases durably reinforces HIV latency.
Schonhofer C, Yi J, Sciorillo A, Andrae-Marobela K, Cochrane A, Harris M, Brumme ZL, Brockman MA, Mounzer K, Hart C, Gyampoh K, Yuan Z, Montaner LJ, Tietjen I. Schonhofer C, et al. Among authors: tietjen i. Biochem Pharmacol. 2021 Apr;186:114462. doi: 10.1016/j.bcp.2021.114462. Epub 2021 Feb 10. Biochem Pharmacol. 2021. PMID: 33577894 Free PMC article.
57 results