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Development of tibulizumab, a tetravalent bispecific antibody targeting BAFF and IL-17A for the treatment of autoimmune disease.
Benschop RJ, Chow CK, Tian Y, Nelson J, Barmettler B, Atwell S, Clawson D, Chai Q, Jones B, Fitchett J, Torgerson S, Ji Y, Bina H, Hu N, Ghanem M, Manetta J, Wroblewski VJ, Lu J, Allan BW. Benschop RJ, et al. Among authors: barmettler b. MAbs. 2019 Aug/Sep;11(6):1175-1190. doi: 10.1080/19420862.2019.1624463. Epub 2019 Jun 10. MAbs. 2019. PMID: 31181988 Free PMC article.
A nondepleting anti-CD19 antibody impairs B cell function and inhibits autoimmune diseases.
Boyles JS, Sadowski D, Potter S, Vukojicic A, Parker J, Chang WY, Ma YL, Chambers MG, Nelson J, Barmettler B, Smith EM, Kersjes K, Himes ER, Lin C, Lucchesi J, Brahmbhatt J, Sina R, Martin JA, Maestri E, Wiethoff CM, Dyas GL, Linnik MD, Na S, Witcher DR, Budelsky A, Rubtsova K. Boyles JS, et al. Among authors: barmettler b. JCI Insight. 2023 Jul 10;8(13):e166137. doi: 10.1172/jci.insight.166137. JCI Insight. 2023. PMID: 37427592 Free PMC article.