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A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia.
Marín-Ramos NI, Balabasquer M, Ortega-Nogales FJ, Torrecillas IR, Gil-Ordóñez A, Marcos-Ramiro B, Aguilar-Garrido P, Cushman I, Romero A, Medrano FJ, Gajate C, Mollinedo F, Philips MR, Campillo M, Gallardo M, Martín-Fontecha M, López-Rodríguez ML, Ortega-Gutiérrez S. Marín-Ramos NI, et al. Among authors: martin fontecha m. J Med Chem. 2019 Jul 11;62(13):6035-6046. doi: 10.1021/acs.jmedchem.9b00145. Epub 2019 Jun 19. J Med Chem. 2019. PMID: 31181882
New inhibitors of angiogenesis with antitumor activity in vivo.
Marín-Ramos NI, Alonso D, Ortega-Gutiérrez S, Ortega-Nogales FJ, Balabasquer M, Vázquez-Villa H, Andradas C, Blasco-Benito S, Pérez-Gómez E, Canales Á, Jiménez-Barbero J, Marquina A, del Prado JM, Sánchez C, Martín-Fontecha M, López-Rodríguez ML. Marín-Ramos NI, et al. J Med Chem. 2015 May 14;58(9):3757-66. doi: 10.1021/jm5019252. Epub 2015 May 4. J Med Chem. 2015. PMID: 25906180
Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling.
Marín-Ramos NI, Piñar C, Vázquez-Villa H, Martín-Fontecha M, González Á, Canales Á, Algar S, Mayo PP, Jiménez-Barbero J, Gajate C, Mollinedo F, Pardo L, Ortega-Gutiérrez S, Viso A, López-Rodríguez ML. Marín-Ramos NI, et al. Chemistry. 2017 Jan 31;23(7):1676-1685. doi: 10.1002/chem.201604905. Epub 2016 Dec 27. Chemistry. 2017. PMID: 27885731 Free article.
Monoacylglycerol lipase (MAGL) as a promising therapeutic target.
Gil-Ordóñez A, Martín-Fontecha M, Ortega-Gutiérrez S, López-Rodríguez ML. Gil-Ordóñez A, et al. Biochem Pharmacol. 2018 Nov;157:18-32. doi: 10.1016/j.bcp.2018.07.036. Epub 2018 Jul 27. Biochem Pharmacol. 2018. PMID: 30059673 Review.
45 results