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Page 1
New pyrazolopyrimidine derivatives as Leishmania amazonensis arginase inhibitors.
Feitosa LM, da Silva ER, Hoelz LVB, Souza DL, Come JAASS, Cardoso-Santos C, Batista MM, Soeiro MNC, Boechat N, Pinheiro LCS. Feitosa LM, et al. Among authors: cardoso santos c. Bioorg Med Chem. 2019 Jul 15;27(14):3061-3069. doi: 10.1016/j.bmc.2019.05.026. Epub 2019 May 17. Bioorg Med Chem. 2019. PMID: 31176565
Drug repurposing strategy against Trypanosoma cruzi infection: In vitro and in vivo assessment of the activity of metronidazole in mono- and combined therapy.
Simões-Silva MR, De Araújo JS, Oliveira GM, Demarque KC, Peres RB, D'Almeida-Melo I, Batista DGJ, Da Silva CF, Cardoso-Santos C, Da Silva PB, Batista MM, Bahia MT, Soeiro MNC. Simões-Silva MR, et al. Among authors: cardoso santos c. Biochem Pharmacol. 2017 Dec 1;145:46-53. doi: 10.1016/j.bcp.2017.08.025. Epub 2017 Sep 7. Biochem Pharmacol. 2017. PMID: 28870526
Evaluation of phthalazinone phosphodiesterase inhibitors with improved activity and selectivity against Trypanosoma cruzi.
De Araújo JS, da Silva PB, Batista MM, Peres RB, Cardoso-Santos C, Kalejaiye TD, Munday JC, De Heuvel E, Sterk GJ, Augustyns K, Salado IG, Matheeussen A, De Esch I, De Koning HP, Leurs R, Maes L, Soeiro MNC. De Araújo JS, et al. Among authors: cardoso santos c. J Antimicrob Chemother. 2020 Apr 1;75(4):958-967. doi: 10.1093/jac/dkz516. J Antimicrob Chemother. 2020. PMID: 31860098
6-Methyl-7-Aryl-7-Deazapurine Nucleosides as Anti-Trypanosoma cruzi Agents: Structure-Activity Relationship and in vivo Efficacy.
Lin C, Ferreira de Almeida Fiuza L, Cardoso Santos C, Ferreira Nunes D, Cruz Moreira O, Bouton J, Karalic I, Maes L, Caljon G, Hulpia F, de Nazaré C Soeiro M, Van Calenbergh S. Lin C, et al. Among authors: cardoso santos c. ChemMedChem. 2021 Jul 20;16(14):2231-2253. doi: 10.1002/cmdc.202100144. Epub 2021 May 13. ChemMedChem. 2021. PMID: 33856742
7-Aryl-7-deazapurine 3'-deoxyribonucleoside derivative as a novel lead for Chagas' disease therapy: in vitro and in vivo pharmacology.
Cardoso-Santos C, Ferreira de Almeida Fiuza L, França da Silva C, Mazzeti AL, Donola Girão R, Melo de Oliveira G, da Gama Jaen Batista D, Cruz Moreira O, Lins da Silva Gomes N, Maes L, Caljon G, Hulpia F, Calenbergh SV, Correia Soeiro MN. Cardoso-Santos C, et al. JAC Antimicrob Resist. 2021 Nov 17;3(4):dlab168. doi: 10.1093/jacamr/dlab168. eCollection 2021 Dec. JAC Antimicrob Resist. 2021. PMID: 34806007 Free PMC article.