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Patient-Derived Cancer Organoid Cultures to Predict Sensitivity to Chemotherapy and Radiation.
Pasch CA, Favreau PF, Yueh AE, Babiarz CP, Gillette AA, Sharick JT, Karim MR, Nickel KP, DeZeeuw AK, Sprackling CM, Emmerich PB, DeStefanis RA, Pitera RT, Payne SN, Korkos DP, Clipson L, Walsh CM, Miller D, Carchman EH, Burkard ME, Lemmon KK, Matkowskyj KA, Newton MA, Ong IM, Bassetti MF, Kimple RJ, Skala MC, Deming DA. Pasch CA, et al. Among authors: nickel kp. Clin Cancer Res. 2019 Sep 1;25(17):5376-5387. doi: 10.1158/1078-0432.CCR-18-3590. Epub 2019 Jun 7. Clin Cancer Res. 2019. PMID: 31175091 Free PMC article.
Radiosensitization of Adenoid Cystic Carcinoma with MDM2 Inhibition.
Prabakaran PJ, Javaid AM, Swick AD, Werner LR, Nickel KP, Sampene E, Hu R, Ong IM, Bruce JY, Hartig GK, Wieland AM, Canon J, Harari PM, Kimple RJ. Prabakaran PJ, et al. Among authors: nickel kp. Clin Cancer Res. 2017 Oct 15;23(20):6044-6053. doi: 10.1158/1078-0432.CCR-17-0969. Epub 2017 Jun 28. Clin Cancer Res. 2017. PMID: 28659312 Free PMC article.
Enhanced radiation sensitivity in HPV-positive head and neck cancer.
Kimple RJ, Smith MA, Blitzer GC, Torres AD, Martin JA, Yang RZ, Peet CR, Lorenz LD, Nickel KP, Klingelhutz AJ, Lambert PF, Harari PM. Kimple RJ, et al. Among authors: nickel kp. Cancer Res. 2013 Aug 1;73(15):4791-800. doi: 10.1158/0008-5472.CAN-13-0587. Epub 2013 Jun 7. Cancer Res. 2013. PMID: 23749640 Free PMC article.
AXL Mediates Cetuximab and Radiation Resistance Through Tyrosine 821 and the c-ABL Kinase Pathway in Head and Neck Cancer.
McDaniel NK, Iida M, Nickel KP, Longhurst CA, Fischbach SR, Rodems TS, Kranjac CA, Bo AY, Luo Q, Gallagher MM, Welke NB, Mitchell KR, Schulz AE, Eckers JC, Hu R, Salgia R, Hong S, Bruce JY, Kimple RJ, Wheeler DL. McDaniel NK, et al. Among authors: nickel kp. Clin Cancer Res. 2020 Aug 15;26(16):4349-4359. doi: 10.1158/1078-0432.CCR-19-3142. Epub 2020 May 21. Clin Cancer Res. 2020. PMID: 32439698 Free PMC article.
Cotargeting mTORC and EGFR Signaling as a Therapeutic Strategy in HNSCC.
Swick AD, Prabakaran PJ, Miller MC, Javaid AM, Fisher MM, Sampene E, Ong IM, Hu R, Iida M, Nickel KP, Bruce JY, Wheeler DL, Kimple RJ. Swick AD, et al. Among authors: nickel kp. Mol Cancer Ther. 2017 Jul;16(7):1257-1268. doi: 10.1158/1535-7163.MCT-17-0115. Epub 2017 Apr 26. Mol Cancer Ther. 2017. PMID: 28446642 Free PMC article.
Patient Derived Models to Study Head and Neck Cancer Radiation Response.
Cosper PF, Abel L, Lee YS, Paz C, Kaushik S, Nickel KP, Alexandridis R, Scott JG, Bruce JY, Kimple RJ. Cosper PF, et al. Among authors: nickel kp. Cancers (Basel). 2020 Feb 12;12(2):419. doi: 10.3390/cancers12020419. Cancers (Basel). 2020. PMID: 32059418 Free PMC article. Review.
FGFR Inhibition Enhances Sensitivity to Radiation in Non-Small Cell Lung Cancer.
SenthilKumar G, Fisher MM, Skiba JH, Miller MC, Brennan SR, Kaushik S, Bradley ST, Longhurst CA, Buehler D, Nickel KP, Iyer G, Kimple RJ, Baschnagel AM. SenthilKumar G, et al. Among authors: nickel kp. Mol Cancer Ther. 2020 Jun;19(6):1255-1265. doi: 10.1158/1535-7163.MCT-19-0931. Epub 2020 May 5. Mol Cancer Ther. 2020. PMID: 32371583 Free PMC article.
ATR Inhibitor M6620 (VX-970) Enhances the Effect of Radiation in Non-Small Cell Lung Cancer Brain Metastasis Patient-Derived Xenografts.
Baschnagel AM, Elnaggar JH, VanBeek HJ, Kromke AC, Skiba JH, Kaushik S, Abel L, Clark PA, Longhurst CA, Nickel KP, Leal TA, Zhao SG, Kimple RJ. Baschnagel AM, et al. Among authors: nickel kp. Mol Cancer Ther. 2021 Nov;20(11):2129-2139. doi: 10.1158/1535-7163.MCT-21-0305. Epub 2021 Aug 19. Mol Cancer Ther. 2021. PMID: 34413128 Free PMC article.
Fibroblast Growth Factor Receptors as Targets for Radiosensitization in Head and Neck Squamous Cell Carcinomas.
Fisher MM, SenthilKumar G, Hu R, Goldstein S, Ong IM, Miller MC, Brennan SR, Kaushik S, Abel L, Nickel KP, Iyer G, Harari PM, Kimple RJ, Baschnagel AM. Fisher MM, et al. Among authors: nickel kp. Int J Radiat Oncol Biol Phys. 2020 Jul 15;107(4):793-803. doi: 10.1016/j.ijrobp.2020.03.040. Epub 2020 Apr 13. Int J Radiat Oncol Biol Phys. 2020. PMID: 32298810 Free PMC article.
40 results