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A validated collection of mouse monoclonal antibodies to human glycosyltransferases functioning in mucin-type O-glycosylation.
Steentoft C, Yang Z, Wang S, Ju T, Vester-Christensen MB, Festari MF, King SL, Moremen K, Larsen ISB, Goth CK, Schjoldager KT, Hansen L, Bennett EP, Mandel U, Narimatsu Y. Steentoft C, et al. Among authors: moremen k. Glycobiology. 2019 Aug 20;29(9):645-656. doi: 10.1093/glycob/cwz041. Glycobiology. 2019. PMID: 31172184 Free PMC article.
The lectin domain of the polypeptide GalNAc transferase family of glycosyltransferases (ppGalNAc Ts) acts as a switch directing glycopeptide substrate glycosylation in an N- or C-terminal direction, further controlling mucin type O-glycosylation.
Gerken TA, Revoredo L, Thome JJ, Tabak LA, Vester-Christensen MB, Clausen H, Gahlay GK, Jarvis DL, Johnson RW, Moniz HA, Moremen K. Gerken TA, et al. Among authors: moremen k. J Biol Chem. 2013 Jul 5;288(27):19900-14. doi: 10.1074/jbc.M113.477877. Epub 2013 May 20. J Biol Chem. 2013. PMID: 23689369 Free PMC article.
221 results