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Systems pharmacology-based integration of human and mouse data for drug repurposing to treat thoracic aneurysms.
Hansen J, Galatioto J, Caescu CI, Arnaud P, Calizo RC, Spronck B, Murtada SI, Borkar R, Weinberg A, Azeloglu EU, Bintanel-Morcillo M, Gallo JM, Humphrey JD, Jondeau G, Boileau C, Ramirez F, Iyengar R. Hansen J, et al. Among authors: murtada si. JCI Insight. 2019 Jun 6;4(11):e127652. doi: 10.1172/jci.insight.127652. eCollection 2019 Jun 6. JCI Insight. 2019. PMID: 31167969 Free PMC article.
Pharmacologically Improved Contractility Protects Against Aortic Dissection in Mice With Disrupted Transforming Growth Factor-β Signaling Despite Compromised Extracellular Matrix Properties.
Ferruzzi J, Murtada SI, Li G, Jiao Y, Uman S, Ting MY, Tellides G, Humphrey JD. Ferruzzi J, et al. Among authors: murtada si. Arterioscler Thromb Vasc Biol. 2016 May;36(5):919-27. doi: 10.1161/ATVBAHA.116.307436. Epub 2016 Mar 17. Arterioscler Thromb Vasc Biol. 2016. PMID: 26988590 Free PMC article.
Smooth Muscle Cell Reprogramming in Aortic Aneurysms.
Chen PY, Qin L, Li G, Malagon-Lopez J, Wang Z, Bergaya S, Gujja S, Caulk AW, Murtada SI, Zhang X, Zhuang ZW, Rao DA, Wang G, Tobiasova Z, Jiang B, Montgomery RR, Sun L, Sun H, Fisher EA, Gulcher JR, Fernandez-Hernando C, Humphrey JD, Tellides G, Chittenden TW, Simons M. Chen PY, et al. Among authors: murtada si. Cell Stem Cell. 2020 Apr 2;26(4):542-557.e11. doi: 10.1016/j.stem.2020.02.013. Cell Stem Cell. 2020. PMID: 32243809 Free PMC article.
Inhibition of HIPK2 Alleviates Thoracic Aortic Disease in Mice With Progressively Severe Marfan Syndrome.
Caescu CI, Hansen J, Crockett B, Xiao W, Arnaud P, Spronck B, Weinberg A, Hashimoto T, Murtada SI, Borkar R, Gallo JM, Jondeau G, Boileau C, Humphrey JD, He JC, Iyengar R, Ramirez F. Caescu CI, et al. Among authors: murtada si. Arterioscler Thromb Vasc Biol. 2021 Sep;41(9):2483-2493. doi: 10.1161/ATVBAHA.121.316464. Epub 2021 Jul 29. Arterioscler Thromb Vasc Biol. 2021. PMID: 34320838 Free PMC article.
32 results