Zhong G - Search Results

1

The retinoic acid hydroxylase Cyp26a1 has minor effects on postnatal vitamin A homeostasis, but is required for exogenous atRA clearance.

Zhong G, Hogarth C, Snyder JM, Palau L, Topping T, Huang W, Czuba LC, LaFrance J, Ghiaur G, Isoherranen N. Zhong G, et al. J Biol Chem. 2019 Jul 19;294(29):11166-11179. doi: 10.1074/jbc.RA119.009023. Epub 2019 Jun 5. J Biol Chem. 2019. PMID: 31167781 Free PMC article.

2

CYP26C1 Is a Hydroxylase of Multiple Active Retinoids and Interacts with Cellular Retinoic Acid Binding Proteins.

Zhong G, Ortiz D, Zelter A, Nath A, Isoherranen N. Zhong G, et al. Mol Pharmacol. 2018 May;93(5):489-503. doi: 10.1124/mol.117.111039. Epub 2018 Feb 23. Mol Pharmacol. 2018. PMID: 29476041 Free PMC article.

3

Sources of all-trans retinal oxidation independent of the aldehyde dehydrogenase 1A isozymes exist in the postnatal testis†.

Beedle MT, Stevison F, Zhong G, Topping T, Hogarth C, Isoherranen N, Griswold MD. Beedle MT, et al. Among authors: zhong g. Biol Reprod. 2019 Feb 1;100(2):547-560. doi: 10.1093/biolre/ioy200. Biol Reprod. 2019. PMID: 30247516 Free PMC article.

4

Commensals Suppress Intestinal Epithelial Cell Retinoic Acid Synthesis to Regulate Interleukin-22 Activity and Prevent Microbial Dysbiosis.

Grizotte-Lake M, Zhong G, Duncan K, Kirkwood J, Iyer N, Smolenski I, Isoherranen N, Vaishnava S. Grizotte-Lake M, et al. Among authors: zhong g. Immunity. 2018 Dec 18;49(6):1103-1115.e6. doi: 10.1016/j.immuni.2018.11.018. Immunity. 2018. PMID: 30566883 Free PMC article.

5

Scaling in vitro activity of CYP3A7 suggests human fetal livers do not clear retinoic acid entering from maternal circulation.

Topletz AR, Zhong G, Isoherranen N. Topletz AR, et al. Among authors: zhong g. Sci Rep. 2019 Mar 15;9(1):4620. doi: 10.1038/s41598-019-40995-8. Sci Rep. 2019. PMID: 30874620 Free PMC article.

6

Characterization of Vitamin A Metabolome in Human Livers With and Without Nonalcoholic Fatty Liver Disease.

Zhong G, Kirkwood J, Won KJ, Tjota N, Jeong H, Isoherranen N. Zhong G, et al. J Pharmacol Exp Ther. 2019 Jul;370(1):92-103. doi: 10.1124/jpet.119.258517. Epub 2019 May 1. J Pharmacol Exp Ther. 2019. PMID: 31043436 Free PMC article.

7

Biochemical and physiological importance of the CYP26 retinoic acid hydroxylases.

Isoherranen N, Zhong G. Isoherranen N, et al. Among authors: zhong g. Pharmacol Ther. 2019 Dec;204:107400. doi: 10.1016/j.pharmthera.2019.107400. Epub 2019 Aug 13. Pharmacol Ther. 2019. PMID: 31419517 Free PMC article. Review.

8

Epithelium intrinsic vitamin A signaling co-ordinates pathogen clearance in the gut via IL-18.

Iyer N, Grizotte-Lake M, Duncan K, Gordon SR, Palmer ACS, Calvin C, Zhong G, Isoherranen N, Vaishnava S. Iyer N, et al. Among authors: zhong g. PLoS Pathog. 2020 Apr 24;16(4):e1008360. doi: 10.1371/journal.ppat.1008360. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32330185 Free PMC article.

9

Analysis of vitamin A and retinoids in biological matrices.

Czuba LC, Zhong G, Yabut KC, Isoherranen N. Czuba LC, et al. Among authors: zhong g. Methods Enzymol. 2020;637:309-340. doi: 10.1016/bs.mie.2020.02.010. Epub 2020 Mar 26. Methods Enzymol. 2020. PMID: 32359651 Free PMC article.

10

Knockout of Cyp26a1 and Cyp26b1 during postnatal life causes reduced lifespan, dermatitis, splenomegaly, and systemic inflammation in mice.

Snyder JM, Zhong G, Hogarth C, Huang W, Topping T, LaFrance J, Palau L, Czuba LC, Griswold M, Ghiaur G, Isoherranen N. Snyder JM, et al. Among authors: zhong g. FASEB J. 2020 Dec;34(12):15788-15804. doi: 10.1096/fj.202001734R. Epub 2020 Oct 26. FASEB J. 2020. PMID: 33105029 Free PMC article.

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