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Mutant Isocitrate Dehydrogenase Inhibitors as Targeted Cancer Therapeutics.
Golub D, Iyengar N, Dogra S, Wong T, Bready D, Tang K, Modrek AS, Placantonakis DG. Golub D, et al. Among authors: modrek as. Front Oncol. 2019 May 17;9:417. doi: 10.3389/fonc.2019.00417. eCollection 2019. Front Oncol. 2019. PMID: 31165048 Free PMC article. Review.
Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2.
Modrek AS, Golub D, Khan T, Bready D, Prado J, Bowman C, Deng J, Zhang G, Rocha PP, Raviram R, Lazaris C, Stafford JM, LeRoy G, Kader M, Dhaliwal J, Bayin NS, Frenster JD, Serrano J, Chiriboga L, Baitalmal R, Nanjangud G, Chi AS, Golfinos JG, Wang J, Karajannis MA, Bonneau RA, Reinberg D, Tsirigos A, Zagzag D, Snuderl M, Skok JA, Neubert TA, Placantonakis DG. Modrek AS, et al. Cell Rep. 2017 Oct 31;21(5):1267-1280. doi: 10.1016/j.celrep.2017.10.009. Cell Rep. 2017. PMID: 29091765 Free PMC article.
Brain stem cells as the cell of origin in glioma.
Modrek AS, Bayin NS, Placantonakis DG. Modrek AS, et al. World J Stem Cells. 2014 Jan 26;6(1):43-52. doi: 10.4252/wjsc.v6.i1.43. World J Stem Cells. 2014. PMID: 24567787 Free PMC article. Review.
Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma.
Stafford JM, Lee CH, Voigt P, Descostes N, Saldaña-Meyer R, Yu JR, Leroy G, Oksuz O, Chapman JR, Suarez F, Modrek AS, Bayin NS, Placantonakis DG, Karajannis MA, Snuderl M, Ueberheide B, Reinberg D. Stafford JM, et al. Among authors: modrek as. Sci Adv. 2018 Oct 31;4(10):eaau5935. doi: 10.1126/sciadv.aau5935. eCollection 2018 Oct. Sci Adv. 2018. PMID: 30402543 Free PMC article.
Selective lentiviral gene delivery to CD133-expressing human glioblastoma stem cells.
Bayin NS, Modrek AS, Dietrich A, Lebowitz J, Abel T, Song HR, Schober M, Zagzag D, Buchholz CJ, Chao MV, Placantonakis DG. Bayin NS, et al. Among authors: modrek as. PLoS One. 2014 Dec 26;9(12):e116114. doi: 10.1371/journal.pone.0116114. eCollection 2014. PLoS One. 2014. PMID: 25541984 Free PMC article.
28 results