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Page 1
Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding.
Gkountela S, Castro-Giner F, Szczerba BM, Vetter M, Landin J, Scherrer R, Krol I, Scheidmann MC, Beisel C, Stirnimann CU, Kurzeder C, Heinzelmann-Schwarz V, Rochlitz C, Weber WP, Aceto N. Gkountela S, et al. Among authors: scheidmann mc. Cell. 2019 Jan 10;176(1-2):98-112.e14. doi: 10.1016/j.cell.2018.11.046. Cell. 2019. PMID: 30633912 Free PMC article.
Neutrophils escort circulating tumour cells to enable cell cycle progression.
Szczerba BM, Castro-Giner F, Vetter M, Krol I, Gkountela S, Landin J, Scheidmann MC, Donato C, Scherrer R, Singer J, Beisel C, Kurzeder C, Heinzelmann-Schwarz V, Rochlitz C, Weber WP, Beerenwinkel N, Aceto N. Szczerba BM, et al. Among authors: scheidmann mc. Nature. 2019 Feb;566(7745):553-557. doi: 10.1038/s41586-019-0915-y. Epub 2019 Feb 6. Nature. 2019. PMID: 30728496
An In Vivo CRISPR Screen Identifies Stepwise Genetic Dependencies of Metastatic Progression.
Scheidmann MC, Castro-Giner F, Strittmatter K, Krol I, Paasinen-Sohns A, Scherrer R, Donato C, Gkountela S, Szczerba BM, Diamantopoulou Z, Muenst S, Vlajnic T, Kunz L, Vetter M, Rochlitz C, Taylor V, Giachino C, Schroeder T, Platt RJ, Aceto N. Scheidmann MC, et al. Cancer Res. 2022 Feb 15;82(4):681-694. doi: 10.1158/0008-5472.CAN-21-3908. Cancer Res. 2022. PMID: 34916221 Free PMC article.
Modularized CRISPR/dCas9 effector toolkit for target-specific gene regulation.
Agne M, Blank I, Emhardt AJ, Gäbelein CG, Gawlas F, Gillich N, Gonschorek P, Juretschke TJ, Krämer SD, Louis N, Müller A, Rudorf A, Schäfer LM, Scheidmann MC, Schmunk LJ, Schwenk PM, Stammnitz MR, Warmer PM, Weber W, Fischer A, Kaufmann B, Wagner HJ, Radziwill G. Agne M, et al. Among authors: scheidmann mc. ACS Synth Biol. 2014 Dec 19;3(12):986-9. doi: 10.1021/sb500035y. ACS Synth Biol. 2014. PMID: 25524106
Arrayed CRISPR libraries for the genome-wide activation, deletion and silencing of human protein-coding genes.
Yin JA, Frick L, Scheidmann MC, Liu T, Trevisan C, Dhingra A, Spinelli A, Wu Y, Yao L, Vena DL, Knapp B, Guo J, De Cecco E, Ging K, Armani A, Oakeley EJ, Nigsch F, Jenzer J, Haegele J, Pikusa M, Täger J, Rodriguez-Nieto S, Bouris V, Ribeiro R, Baroni F, Bedi MS, Berry S, Losa M, Hornemann S, Kampmann M, Pelkmans L, Hoepfner D, Heutink P, Aguzzi A. Yin JA, et al. Among authors: scheidmann mc. Nat Biomed Eng. 2025 Jan;9(1):127-148. doi: 10.1038/s41551-024-01278-4. Epub 2024 Dec 4. Nat Biomed Eng. 2025. PMID: 39633028 Free PMC article.
MyCTC chip: microfluidic-based drug screen with patient-derived tumour cells from liquid biopsies.
Schwab FD, Scheidmann MC, Ozimski LL, Kling A, Armbrecht L, Ryser T, Krol I, Strittmatter K, Nguyen-Sträuli BD, Jacob F, Fedier A, Heinzelmann-Schwarz V, Wicki A, Dittrich PS, Aceto N. Schwab FD, et al. Among authors: scheidmann mc. Microsyst Nanoeng. 2022 Dec 20;8:130. doi: 10.1038/s41378-022-00467-y. eCollection 2022. Microsyst Nanoeng. 2022. PMID: 36561926 Free PMC article.