Patel DJ - Search Results

1

Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.

Xie W, Lama L, Adura C, Tomita D, Glickman JF, Tuschl T, Patel DJ. Xie W, et al. Among authors: patel dj. Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11946-11955. doi: 10.1073/pnas.1905013116. Epub 2019 May 29. Proc Natl Acad Sci U S A. 2019. PMID: 31142647 Free PMC article.

2

An interlocked dimeric parallel-stranded DNA quadruplex: a potent inhibitor of HIV-1 integrase.

Phan AT, Kuryavyi V, Ma JB, Faure A, Andréola ML, Patel DJ. Phan AT, et al. Among authors: patel dj. Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):634-9. doi: 10.1073/pnas.0406278102. Epub 2005 Jan 6. Proc Natl Acad Sci U S A. 2005. PMID: 15637158 Free PMC article.

3

Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein.

Ma JB, Yuan YR, Meister G, Pei Y, Tuschl T, Patel DJ. Ma JB, et al. Among authors: patel dj. Nature. 2005 Mar 31;434(7033):666-70. doi: 10.1038/nature03514. Nature. 2005. PMID: 15800629 Free PMC article.

4

Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage.

Yuan YR, Pei Y, Ma JB, Kuryavyi V, Zhadina M, Meister G, Chen HY, Dauter Z, Tuschl T, Patel DJ. Yuan YR, et al. Among authors: patel dj. Mol Cell. 2005 Aug 5;19(3):405-19. doi: 10.1016/j.molcel.2005.07.011. Mol Cell. 2005. PMID: 16061186 Free PMC article.

5

A potential protein-RNA recognition event along the RISC-loading pathway from the structure of A. aeolicus Argonaute with externally bound siRNA.

Yuan YR, Pei Y, Chen HY, Tuschl T, Patel DJ. Yuan YR, et al. Among authors: patel dj. Structure. 2006 Oct;14(10):1557-65. doi: 10.1016/j.str.2006.08.009. Structure. 2006. PMID: 17027504 Free PMC article.

6

Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense.

Zhang X, Yuan YR, Pei Y, Lin SS, Tuschl T, Patel DJ, Chua NH. Zhang X, et al. Among authors: patel dj. Genes Dev. 2006 Dec 1;20(23):3255-68. doi: 10.1101/gad.1495506. Genes Dev. 2006. PMID: 17158744 Free PMC article.

7

Structural biology of RNA silencing and its functional implications.

Patel DJ, Ma JB, Yuan YR, Ye K, Pei Y, Kuryavyi V, Malinina L, Meister G, Tuschl T. Patel DJ, et al. Cold Spring Harb Symp Quant Biol. 2006;71:81-93. doi: 10.1101/sqb.2006.71.053. Cold Spring Harb Symp Quant Biol. 2006. PMID: 17381284 Free PMC article. Review.

8

Structure of the guide-strand-containing argonaute silencing complex.

Wang Y, Sheng G, Juranek S, Tuschl T, Patel DJ. Wang Y, et al. Among authors: patel dj. Nature. 2008 Nov 13;456(7219):209-13. doi: 10.1038/nature07315. Epub 2008 Aug 27. Nature. 2008. PMID: 18754009 Free PMC article.

9

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex.

Wang Y, Juranek S, Li H, Sheng G, Tuschl T, Patel DJ. Wang Y, et al. Among authors: patel dj. Nature. 2008 Dec 18;456(7224):921-6. doi: 10.1038/nature07666. Nature. 2008. PMID: 19092929 Free PMC article.

10

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.

Wang Y, Juranek S, Li H, Sheng G, Wardle GS, Tuschl T, Patel DJ. Wang Y, et al. Among authors: patel dj. Nature. 2009 Oct 8;461(7265):754-61. doi: 10.1038/nature08434. Nature. 2009. PMID: 19812667 Free PMC article.

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