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Page 1
Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi®.
Taylor JG, Zipfel S, Ramey K, Vivian R, Schrier A, Karki KK, Katana A, Kato D, Kobayashi T, Martinez R, Sangi M, Siegel D, Tran CV, Yang ZY, Zablocki J, Yang CY, Wang Y, Wang K, Chan K, Barauskas O, Cheng G, Jin D, Schultz BE, Appleby T, Villaseñor AG, Link JO. Taylor JG, et al. Among authors: zipfel s. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2428-2436. doi: 10.1016/j.bmcl.2019.03.037. Epub 2019 Mar 26. Bioorg Med Chem Lett. 2019. PMID: 31133531
Discovery of velpatasvir (GS-5816): A potent pan-genotypic HCV NS5A inhibitor in the single-tablet regimens Vosevi® and Epclusa®.
Link JO, Taylor JG, Trejo-Martin A, Kato D, Katana AA, Krygowski ES, Yang ZY, Zipfel S, Cottell JJ, Bacon EM, Tran CV, Yang CY, Wang Y, Wang KW, Zhao G, Cheng G, Tian Y, Gong R, Lee YJ, Yu M, Gorman E, Mogalian E, Perry JK. Link JO, et al. Among authors: zipfel s. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2415-2427. doi: 10.1016/j.bmcl.2019.04.027. Epub 2019 May 4. Bioorg Med Chem Lett. 2019. PMID: 31230974
Advances in cathepsin S inhibitor design.
Link JO, Zipfel S. Link JO, et al. Among authors: zipfel s. Curr Opin Drug Discov Devel. 2006 Jul;9(4):471-82. Curr Opin Drug Discov Devel. 2006. PMID: 16889230 Review.
Discovery of S-[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxypropoxy)phenyl]methanone (RO3201195), an orally bioavailable and highly selective inhibitor of p38 MAP kinase.
Goldstein DM, Alfredson T, Bertrand J, Browner MF, Clifford K, Dalrymple SA, Dunn J, Freire-Moar J, Harris S, Labadie SS, La Fargue J, Lapierre JM, Larrabee S, Li F, Papp E, McWeeney D, Ramesha C, Roberts R, Rotstein D, San Pablo B, Sjogren EB, So OY, Talamas FX, Tao W, Trejo A, Villasenor A, Welch M, Welch T, Weller P, Whiteley PE, Young K, Zipfel S. Goldstein DM, et al. Among authors: zipfel s. J Med Chem. 2006 Mar 9;49(5):1562-75. doi: 10.1021/jm050736c. J Med Chem. 2006. PMID: 16509574
Identification of orally-bioavailable antagonists of the TRPV4 ion-channel.
Wei ZL, Nguyen MT, O'Mahony DJ, Acevedo A, Zipfel S, Zhang Q, Liu L, Dourado M, Chi C, Yip V, DeFalco J, Gustafson A, Emerling DE, Kelly MG, Kincaid J, Vincent F, Duncton MA. Wei ZL, et al. Among authors: zipfel s. Bioorg Med Chem Lett. 2015 Sep 15;25(18):4011-5. doi: 10.1016/j.bmcl.2015.06.098. Epub 2015 Jul 6. Bioorg Med Chem Lett. 2015. PMID: 26235950
Genetic and functional analyses of CTBP2 in anorexia nervosa and body weight regulation.
Giuranna J, Zheng Y, Brandt M, Jall S, Mukherjee A, Shankhwar S, Renner S, Kurapati NK, May C, Peters T, Herpertz-Dahlmann B, Seitz J, de Zwaan M, Herzog W, Ehrlich S, Zipfel S, Giel K, Egberts K, Burghardt R, Föcker M, Marcus K, Keyvani K, Müller TD, Schmitz F, Rajcsanyi LS, Hinney A. Giuranna J, et al. Among authors: zipfel s. Mol Psychiatry. 2024 Nov 7. doi: 10.1038/s41380-024-02791-3. Online ahead of print. Mol Psychiatry. 2024. PMID: 39511451
The interplay of personality pathology and treatment outcome in psychosomatic psychotherapy: A longitudinal analysis using latent change score modelling.
Bierling AL, Doering S, Weidner K, Pape M, Kessler H, Hofmann T, Rose M, Imbierowicz K, Geiser F, Rademacher J, Michalek S, Morawa E, Erim Y, Schneider JS, Teufel M, Hartmann A, Lahmann C, Peters EMJ, Kruse J, von Boetticher D, Herrmann-Lingen C, Nöhre M, de Zwaan M, Dinger U, Friederich HC, Niecke A, Albus C, Zwerenz R, Beutel M, Sattel HC, Henningsen P, Stein B, Waller C, Hake K, Spitzer C, Stengel A, Zipfel S, Weimer K, Gündel H, Herpertz S, Croy I. Bierling AL, et al. Among authors: zipfel s. Compr Psychiatry. 2024 Nov;135:152532. doi: 10.1016/j.comppsych.2024.152532. Epub 2024 Sep 23. Compr Psychiatry. 2024. PMID: 39341174 Free article.
567 results