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Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.
Zhang Y, Jang Y, Lee JE, Ahn J, Xu L, Holden MR, Cornett EM, Krajewski K, Klein BJ, Wang SP, Dou Y, Roeder RG, Strahl BD, Rothbart SB, Shi X, Ge K, Kutateladze TG. Zhang Y, et al. Among authors: xu l. Nat Commun. 2019 May 24;10(1):2314. doi: 10.1038/s41467-019-10324-8. Nat Commun. 2019. PMID: 31127101 Free PMC article.
Discovery of Selective Small-Molecule Inhibitors for the ENL YEATS Domain.
Ma XR, Xu L, Xu S, Klein BJ, Wang H, Das S, Li K, Yang KS, Sohail S, Chapman A, Kutateladze TG, Shi X, Liu WR, Wen H. Ma XR, et al. Among authors: xu l, xu s. J Med Chem. 2021 Aug 12;64(15):10997-11013. doi: 10.1021/acs.jmedchem.1c00367. Epub 2021 Jul 19. J Med Chem. 2021. PMID: 34279931 Free PMC article.
Histone H4K16ac Binding Function of the Triple PHD Finger Cassette of MLL4.
Kumar Sinha V, Zhang Y, Xu L, Chen YW, Picaud S, Zandian M, Biswas S, Filippakopoulos P, Wang SP, Shi X, Kutateladze TG. Kumar Sinha V, et al. Among authors: xu l. J Mol Biol. 2024 Apr 1;436(7):168212. doi: 10.1016/j.jmb.2023.168212. Epub 2023 Jul 20. J Mol Biol. 2024. PMID: 37481158
CCN5 suppresses injury-induced vascular restenosis by inhibiting smooth muscle cell proliferation and facilitating endothelial repair via thymosin β4 and Cd9 pathway.
Zhang Q, Li H, Zhuang T, Xu L, Wu W, Pi J, Zhu P, Geng L, Duan Y, Xu J, Yue J, Liu X, He C, Chen X, Ruan C, Zhuang S, Liu Z, Wang Y, Zhang L, Liu J, Zhang Y. Zhang Q, et al. Among authors: xu l. Eur Heart J. 2025 Jan 28:ehae911. doi: 10.1093/eurheartj/ehae911. Online ahead of print. Eur Heart J. 2025. PMID: 39873228
Getah virus triggers ROS-mediated autophagy in mouse Leydig cells.
Li F, Deng L, Xu T, Xu L, Xu Z, Lai S, Ai Y, Wang Y, Yan G, Zhu L. Li F, et al. Among authors: xu l. Front Microbiol. 2025 Jan 13;15:1519694. doi: 10.3389/fmicb.2024.1519694. eCollection 2024. Front Microbiol. 2025. PMID: 39872815 Free PMC article.
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