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Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations.
Wilmes S, Hafer M, Vuorio J, Tucker JA, Winkelmann H, Löchte S, Stanly TA, Pulgar Prieto KD, Poojari C, Sharma V, Richter CP, Kurre R, Hubbard SR, Garcia KC, Moraga I, Vattulainen I, Hitchcock IS, Piehler J. Wilmes S, et al. Among authors: hafer m. Science. 2020 Feb 7;367(6478):643-652. doi: 10.1126/science.aaw3242. Science. 2020. PMID: 32029621 Free PMC article.
Organizing structural principles of the IL-17 ligand-receptor axis.
Wilson SC, Caveney NA, Yen M, Pollmann C, Xiang X, Jude KM, Hafer M, Tsutsumi N, Piehler J, Garcia KC. Wilson SC, et al. Among authors: hafer m. Nature. 2022 Sep;609(7927):622-629. doi: 10.1038/s41586-022-05116-y. Epub 2022 Jul 21. Nature. 2022. PMID: 35863378 Free PMC article.
Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Tsirigotaki A, Dansercoer A, Verschueren KHG, Marković I, Pollmann C, Hafer M, Felix J, Birck C, Van Putte W, Catteeuw D, Tavernier J, Fernando Bazan J, Piehler J, Savvides SN, Verstraete K. Tsirigotaki A, et al. Among authors: hafer m. Nat Struct Mol Biol. 2023 Apr;30(4):551-563. doi: 10.1038/s41594-023-00941-9. Epub 2023 Mar 23. Nat Struct Mol Biol. 2023. PMID: 36959263
24 results