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A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response.
Koday MT, Nelson J, Chevalier A, Koday M, Kalinoski H, Stewart L, Carter L, Nieusma T, Lee PS, Ward AB, Wilson IA, Dagley A, Smee DF, Baker D, Fuller DH. Koday MT, et al. Among authors: baker d. PLoS Pathog. 2016 Feb 4;12(2):e1005409. doi: 10.1371/journal.ppat.1005409. eCollection 2016 Feb. PLoS Pathog. 2016. PMID: 26845438 Free PMC article.
Accurate computational design of multipass transmembrane proteins.
Lu P, Min D, DiMaio F, Wei KY, Vahey MD, Boyken SE, Chen Z, Fallas JA, Ueda G, Sheffler W, Mulligan VK, Xu W, Bowie JU, Baker D. Lu P, et al. Among authors: baker d. Science. 2018 Mar 2;359(6379):1042-1046. doi: 10.1126/science.aaq1739. Science. 2018. PMID: 29496880 Free PMC article.
Programmable design of orthogonal protein heterodimers.
Chen Z, Boyken SE, Jia M, Busch F, Flores-Solis D, Bick MJ, Lu P, VanAernum ZL, Sahasrabuddhe A, Langan RA, Bermeo S, Brunette TJ, Mulligan VK, Carter LP, DiMaio F, Sgourakis NG, Wysocki VH, Baker D. Chen Z, et al. Among authors: baker d. Nature. 2019 Jan;565(7737):106-111. doi: 10.1038/s41586-018-0802-y. Epub 2018 Dec 19. Nature. 2019. PMID: 30568301 Free PMC article.
Self-Assembling 2D Arrays with de Novo Protein Building Blocks.
Chen Z, Johnson MC, Chen J, Bick MJ, Boyken SE, Lin B, De Yoreo JJ, Kollman JM, Baker D, DiMaio F. Chen Z, et al. Among authors: baker d. J Am Chem Soc. 2019 Jun 5;141(22):8891-8895. doi: 10.1021/jacs.9b01978. Epub 2019 May 10. J Am Chem Soc. 2019. PMID: 31050411 Free PMC article.
De novo design of tunable, pH-driven conformational changes.
Boyken SE, Benhaim MA, Busch F, Jia M, Bick MJ, Choi H, Klima JC, Chen Z, Walkey C, Mileant A, Sahasrabuddhe A, Wei KY, Hodge EA, Byron S, Quijano-Rubio A, Sankaran B, King NP, Lippincott-Schwartz J, Wysocki VH, Lee KK, Baker D. Boyken SE, et al. Among authors: baker d. Science. 2019 May 17;364(6441):658-664. doi: 10.1126/science.aav7897. Science. 2019. PMID: 31097662 Free PMC article.
Protein interaction networks revealed by proteome coevolution.
Cong Q, Anishchenko I, Ovchinnikov S, Baker D. Cong Q, et al. Among authors: baker d. Science. 2019 Jul 12;365(6449):185-189. doi: 10.1126/science.aaw6718. Epub 2019 Jul 11. Science. 2019. PMID: 31296772 Free PMC article.
High-accuracy refinement using Rosetta in CASP13.
Park H, Lee GR, Kim DE, Anishchenko I, Cong Q, Baker D. Park H, et al. Among authors: baker d. Proteins. 2019 Dec;87(12):1276-1282. doi: 10.1002/prot.25784. Epub 2019 Aug 5. Proteins. 2019. PMID: 31325340 Free PMC article.
5,808 results