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Sialyltransferase inhibition leads to inhibition of tumor cell interactions with E-selectin, VCAM1, and MADCAM1, and improves survival in a human multiple myeloma mouse model.
Natoni A, Farrell ML, Harris S, Falank C, Kirkham-McCarthy L, Macauley MS, Reagan MR, O'Dwyer M. Natoni A, et al. Among authors: farrell ml. Haematologica. 2020 Jan 31;105(2):457-467. doi: 10.3324/haematol.2018.212266. Print 2020. Haematologica. 2020. PMID: 31101754 Free PMC article.
Development of a 3D bone marrow adipose tissue model.
Fairfield H, Falank C, Farrell M, Vary C, Boucher JM, Driscoll H, Liaw L, Rosen CJ, Reagan MR. Fairfield H, et al. Bone. 2019 Jan;118:77-88. doi: 10.1016/j.bone.2018.01.023. Epub 2018 Jan 31. Bone. 2019. PMID: 29366838 Free PMC article.
Myeloma-Modified Adipocytes Exhibit Metabolic Dysfunction and a Senescence-Associated Secretory Phenotype.
Fairfield H, Dudakovic A, Khatib CM, Farrell M, Costa S, Falank C, Hinge M, Murphy CS, DeMambro V, Pettitt JA, Lary CW, Driscoll HE, McDonald MM, Kassem M, Rosen C, Andersen TL, van Wijnen AJ, Jafari A, Reagan MR. Fairfield H, et al. Cancer Res. 2021 Feb 1;81(3):634-647. doi: 10.1158/0008-5472.CAN-20-1088. Epub 2020 Nov 20. Cancer Res. 2021. PMID: 33218968 Free PMC article.
64 results