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Sialyltransferase inhibition leads to inhibition of tumor cell interactions with E-selectin, VCAM1, and MADCAM1, and improves survival in a human multiple myeloma mouse model.
Natoni A, Farrell ML, Harris S, Falank C, Kirkham-McCarthy L, Macauley MS, Reagan MR, O'Dwyer M. Natoni A, et al. Among authors: falank c. Haematologica. 2020 Jan 31;105(2):457-467. doi: 10.3324/haematol.2018.212266. Print 2020. Haematologica. 2020. PMID: 31101754 Free PMC article.
Multiple myeloma in the marrow: pathogenesis and treatments.
Fairfield H, Falank C, Avery L, Reagan MR. Fairfield H, et al. Among authors: falank c. Ann N Y Acad Sci. 2016 Jan;1364(1):32-51. doi: 10.1111/nyas.13038. Ann N Y Acad Sci. 2016. PMID: 27002787 Free PMC article. Review.
Adipose, Bone, and Myeloma: Contributions from the Microenvironment.
McDonald MM, Fairfield H, Falank C, Reagan MR. McDonald MM, et al. Among authors: falank c. Calcif Tissue Int. 2017 May;100(5):433-448. doi: 10.1007/s00223-016-0162-2. Epub 2016 Jun 24. Calcif Tissue Int. 2017. PMID: 27343063 Free PMC article. Review.
Tissue-engineered 3D cancer-in-bone modeling: silk and PUR protocols.
Dadwal U, Falank C, Fairfield H, Linehan S, Rosen CJ, Kaplan DL, Sterling J, Reagan MR. Dadwal U, et al. Among authors: falank c. Bonekey Rep. 2016 Oct 19;5:842. doi: 10.1038/bonekey.2016.75. eCollection 2016. Bonekey Rep. 2016. PMID: 27790370 Free PMC article.
The skeletal cell-derived molecule sclerostin drives bone marrow adipogenesis.
Fairfield H, Falank C, Harris E, Demambro V, McDonald M, Pettitt JA, Mohanty ST, Croucher P, Kramer I, Kneissel M, Rosen CJ, Reagan MR. Fairfield H, et al. Among authors: falank c. J Cell Physiol. 2018 Feb;233(2):1156-1167. doi: 10.1002/jcp.25976. Epub 2017 Jun 6. J Cell Physiol. 2018. PMID: 28460416 Free PMC article.
Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma.
McDonald MM, Reagan MR, Youlten SE, Mohanty ST, Seckinger A, Terry RL, Pettitt JA, Simic MK, Cheng TL, Morse A, Le LMT, Abi-Hanna D, Kramer I, Falank C, Fairfield H, Ghobrial IM, Baldock PA, Little DG, Kneissel M, Vanderkerken K, Bassett JHD, Williams GR, Oyajobi BO, Hose D, Phan TG, Croucher PI. McDonald MM, et al. Among authors: falank c. Blood. 2017 Jun 29;129(26):3452-3464. doi: 10.1182/blood-2017-03-773341. Epub 2017 May 17. Blood. 2017. PMID: 28515094 Free PMC article.
Metformin Affects Cortical Bone Mass and Marrow Adiposity in Diet-Induced Obesity in Male Mice.
Bornstein S, Moschetta M, Kawano Y, Sacco A, Huynh D, Brooks D, Manier S, Fairfield H, Falank C, Roccaro AM, Nagano K, Baron R, Bouxein M, Vary C, Ghobrial IM, Rosen CJ, Reagan MR. Bornstein S, et al. Among authors: falank c. Endocrinology. 2017 Oct 1;158(10):3369-3385. doi: 10.1210/en.2017-00299. Endocrinology. 2017. PMID: 28977604 Free PMC article.
Development of a 3D bone marrow adipose tissue model.
Fairfield H, Falank C, Farrell M, Vary C, Boucher JM, Driscoll H, Liaw L, Rosen CJ, Reagan MR. Fairfield H, et al. Among authors: falank c. Bone. 2019 Jan;118:77-88. doi: 10.1016/j.bone.2018.01.023. Epub 2018 Jan 31. Bone. 2019. PMID: 29366838 Free PMC article.
49 results