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Phospholipase Cgamma1 is required for metastasis development and progression.
Sala G, Dituri F, Raimondi C, Previdi S, Maffucci T, Mazzoletti M, Rossi C, Iezzi M, Lattanzio R, Piantelli M, Iacobelli S, Broggini M, Falasca M. Sala G, et al. Among authors: iacobelli s. Cancer Res. 2008 Dec 15;68(24):10187-96. doi: 10.1158/0008-5472.CAN-08-1181. Cancer Res. 2008. PMID: 19074886
ErbB-3 activation by NRG-1β sustains growth and promotes vemurafenib resistance in BRAF-V600E colon cancer stem cells (CSCs).
Prasetyanti PR, Capone E, Barcaroli D, D'Agostino D, Volpe S, Benfante A, van Hooff S, Iacobelli V, Rossi C, Iacobelli S, Medema JP, De Laurenzi V, Sala G. Prasetyanti PR, et al. Among authors: iacobelli v, iacobelli s. Oncotarget. 2015 Jul 10;6(19):16902-11. doi: 10.18632/oncotarget.4642. Oncotarget. 2015. PMID: 26160848 Free PMC article.
Overexpression of activated phospholipase Cγ1 is a risk factor for distant metastases in T1-T2, N0 breast cancer patients undergoing adjuvant chemotherapy.
Lattanzio R, Marchisio M, La Sorda R, Tinari N, Falasca M, Alberti S, Miscia S, Ercolani C, Di Benedetto A, Perracchio L, Melucci E, Iacobelli S, Mottolese M, Natali PG, Piantelli M; CINBO (Consorzio Interuniversitario Nazionale per Bio-Oncologia). Lattanzio R, et al. Among authors: iacobelli s. Int J Cancer. 2013 Mar 1;132(5):1022-31. doi: 10.1002/ijc.27751. Epub 2012 Sep 1. Int J Cancer. 2013. PMID: 22847294
475 results