Falasca M - Search Results

1

Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer.

Emmanouilidi A, Fyffe CA, Ferro R, Edling CE, Capone E, Sestito S, Rapposelli S, Lattanzio R, Iacobelli S, Sala G, Maffucci T, Falasca M. Emmanouilidi A, et al. Among authors: falasca m. J Exp Clin Cancer Res. 2019 May 14;38(1):191. doi: 10.1186/s13046-019-1191-2. J Exp Clin Cancer Res. 2019. PMID: 31088502 Free PMC article.

2

Specificity in pleckstrin homology (PH) domain membrane targeting: a role for a phosphoinositide-protein co-operative mechanism.

Maffucci T, Falasca M. Maffucci T, et al. Among authors: falasca m. FEBS Lett. 2001 Oct 12;506(3):173-9. doi: 10.1016/s0014-5793(01)02909-x. FEBS Lett. 2001. PMID: 11602240 Free article. Review.

3

The mechanism involved in the regulation of phospholipase Cgamma1 activity in cell migration.

Piccolo E, Innominato PF, Mariggio MA, Maffucci T, Iacobelli S, Falasca M. Piccolo E, et al. Among authors: falasca m. Oncogene. 2002 Sep 19;21(42):6520-9. doi: 10.1038/sj.onc.1205821. Oncogene. 2002. PMID: 12226755

4

Role of pleckstrin homology domain in regulating membrane targeting and metabolic function of insulin receptor substrate 3.

Maffucci T, Razzini G, Ingrosso A, Chen H, Iacobelli S, Sciacchitano S, Quon MJ, Falasca M. Maffucci T, et al. Among authors: falasca m. Mol Endocrinol. 2003 Aug;17(8):1568-79. doi: 10.1210/me.2001-0211. Epub 2003 May 8. Mol Endocrinol. 2003. PMID: 12738760

5

Insulin induces phosphatidylinositol-3-phosphate formation through TC10 activation.

Maffucci T, Brancaccio A, Piccolo E, Stein RC, Falasca M. Maffucci T, et al. Among authors: falasca m. EMBO J. 2003 Aug 15;22(16):4178-89. doi: 10.1093/emboj/cdg402. EMBO J. 2003. PMID: 12912916 Free PMC article.

6

Inositol pentakisphosphate promotes apoptosis through the PI 3-K/Akt pathway.

Piccolo E, Vignati S, Maffucci T, Innominato PF, Riley AM, Potter BV, Pandolfi PP, Broggini M, Iacobelli S, Innocenti P, Falasca M. Piccolo E, et al. Among authors: falasca m. Oncogene. 2004 Mar 4;23(9):1754-65. doi: 10.1038/sj.onc.1207296. Oncogene. 2004. PMID: 14755253

7

Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration.

Maffucci T, Cooke FT, Foster FM, Traer CJ, Fry MJ, Falasca M. Maffucci T, et al. Among authors: falasca m. J Cell Biol. 2005 Jun 6;169(5):789-99. doi: 10.1083/jcb.200408005. Epub 2005 May 31. J Cell Biol. 2005. PMID: 15928202 Free PMC article.

8

Inhibition of the phosphatidylinositol 3-kinase/Akt pathway by inositol pentakisphosphate results in antiangiogenic and antitumor effects.

Maffucci T, Piccolo E, Cumashi A, Iezzi M, Riley AM, Saiardi A, Godage HY, Rossi C, Broggini M, Iacobelli S, Potter BV, Innocenti P, Falasca M. Maffucci T, et al. Among authors: falasca m. Cancer Res. 2005 Sep 15;65(18):8339-49. doi: 10.1158/0008-5472.CAN-05-0121. Cancer Res. 2005. PMID: 16166311

9

Emerging roles of phosphatidylinositol 3-monophosphate as a dynamic lipid second messenger.

Falasca M, Maffucci T. Falasca M, et al. Arch Physiol Biochem. 2006 Oct-Dec;112(4-5):274-84. doi: 10.1080/13813450601094664. Arch Physiol Biochem. 2006. PMID: 17178602 Review.

10

Role of class II phosphoinositide 3-kinase in cell signalling.

Falasca M, Maffucci T. Falasca M, et al. Biochem Soc Trans. 2007 Apr;35(Pt 2):211-4. doi: 10.1042/BST0350211. Biochem Soc Trans. 2007. PMID: 17371240 Review.

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